My white cell count is down and my GP says havi... - Thyroid UK

Thyroid UK

137,936 members161,765 posts

My white cell count is down and my GP says having too higher dose of thyroxine could cause this but he's taken no action, should I go back?

Lee20 profile image
7 Replies
Written by
Lee20 profile image
Lee20
To view profiles and participate in discussions please or .
Read more about...
7 Replies
Heloise profile image
Heloise

You certainly have the right to know your free T3 level which will tell you whether you are overmedicating if that is his theory. There might be other reasons for a low white count and he should name those for you as well.

Lee20 profile image
Lee20

Thanks, Heloise, he has indicated that blood results show I'm being over medicated but he gave me a 12 month review date. However, having had a day of feeling exhausted with aching joints, I have my doubts about waiting 12 months.

Heloise profile image
Heloise in reply to Lee20

Here are come other causes other than a disease like lupus or an infection:

Medications which can cause leukopenia include clozapine, an antipsychotic medication with a rare adverse effect leading to the total absence of all granulocytes (neutrophils, basophils, eosinophils). The antidepressant and smoking addiction treatment drug bupropion HCl (Wellbutrin) can also cause leukopenia with long-term use. Minocycline, a commonly prescribed antibiotic, is another drug known to cause leukopenia. There are also reports of leukopenia caused by divalproex sodium or valproic acid (Depakote), a drug used for epilepsy (seizures), mania (with bipolar disorder) and migraine.

The anticonvulsant drug, lamotrigine, has been associated with a decrease in white blood cell count.[1]

The FDA monograph for metronidazole states that this medication can also cause leukopenia, and the prescriber information suggests a complete blood count, including differential cell count, before and after, in particular, high dose therapy.

Angela profile image
Angela

Sorry for being a bit thick when you say white cell count is low would that be the same as platelet s ????

Heloise profile image
Heloise in reply to Angela

No, Angela, different. Platelets, or thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are small, disk shaped clear cell fragments (i.e. cells that do not have a nucleus), 2–3 µm in diameter,[1] which are derived from fragmentation of precursor megakaryocytes. The average lifespan of a platelet is normally just 5 to 9 days. Platelets are a natural source of growth

Glynisrose profile image
Glynisrose

How do you feel? Doctors soon jump on 'overmedicated' when the TSH is supressed but it is very common and causes less damage.

Lee20 profile image
Lee20

Hi, thanks for responses, I've spoken to my doctor and he's told me stop the Lansoprazole that I take due to a hiatus hernia and he says that will help the white cell count. He still isn't listening to my stating I get very tired but at least now he's going to review me in a month, so I'll see how things go. Thanks again.

You may also like...