Experiences with

Osteogenesis imperfecta

imperfecta (brittle bones)

Bisphosphonates can be administered orally or parenterally.Oral administration is indicated for osteoporosis, osteopenia, Paget’s disease, and osteogenesis imperfecta [26], as well as in the treatment of chronic kidney disease, kidney transplantation, rheumatoid diseases associated with systemic bone

He had a genetic test for osteogenesis imperfecta and came back with 2 variants of uncertain significance in LRP5 gene and P4HB gene. His dad and I were both tested for those genes and we carry one each. His dad has the LRP5 gene which is a bone affecting gene.

Highlights • Chest deformities in Osteogenesis Imperfecta patients affect pulmonary function. • We present the rib cage deformities related to pulmonary function. • There are significant relations between ribs shape and spirometric parameters. • There is no relationship between thoracic spine shape

A friend’s daughter has OI. Anyone with OI can you please reach out.

There is also Osteogenesis Imperfecta. Families have been broken up, false accusations, parents imprisoned. It is only when people stand up and speak out. Someone needs to take notice and put a stop to all of the heartbreak. Stand up and speak out.