Experiences with
Ortho Tri-Cyclen167 public posts
Dentifrice Reducing Levothyroxine Efficacy in Children
A potentially important issue for some people.
And one that is 100% ignored when dentists say we should not rinse after brushing. Even if we do rinse after some time, it is likely that we will swallow some of the calcium ingredients (if our toothpaste contains any).
Despite being written as a paediatric
Hypothyroidism is a causal determinant of age-related cataract risk in European population: a Mendelian randomization study
If you search this forum, you can find 52 posts which mention "cataract" - and several gave rise to significant discussions.
Search if you wish:
https://healthunlocked.com/thyroiduk/search/posts?query=cataract
I'm not sure how much "proof" this paper provides of a link. But it certainly points a finger
American Thyroid Association - Thyroid Hormone Testing overview
Like most documents, this has strengths and weaknesses.
You might find it easier to follow than some. Though some of it really is quite hard for those not already familiar with thyroid issues.
Or more up-to-date (it was published this year - 2024).
And it might provide some useful and quotable
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US-based, Prospective, Blinded Study of Thyrotropin Receptor Antibody in Autoimmune Thyroid Disease
A rather disappointing paper. First, the full paper is, as so often, behind a paywall.
Also, because the the paper doesn't come out with a clear "Yes, the tests are wonderful and reliable."
It is quite clear that there is sufficient uncertainty to question all results from these tests.
We have had
Takotsubo syndrome outcomes predicted by thyroid hormone signature: insights from cluster analysis of a multicentre registry
Brand new paper from Johannes Dietrich (one of diogenes' group) and others.
[i]What is takotsubo cardiomyopathy?[/i]
[i]British Heart Foundation[/i]
https://www.bhf.org.uk/informationsupport/conditions/cardiomyopathy/takotsubo-cardiomyopathy
[i]Takotsubo syndrome outcomes predicted by
Preconception Thyrotropin Levels and Thyroid Function at Early Gestation in Women With Hashimoto Thyroiditis
Of course, research is necessary. We can all make lots of assumptions, guesses, which turn out to be entirely wrong. But this paper does seem to endorse what many here have said.
If you are going to become pregnant, that itself will tend to raise TSH levels.
If you want to keep below any chosen TSH
Computer-Assisted Levothyroxine Dose Selection for the Treatment of Postoperative Hypothyroidism
A paper which causes me significant concern.
This is my blog which explains, I hope, my deep scepticism about existing prediction of required levothyroxine doses.
[i] helvella - Estimation of Levothyroxine Dosing in Adults
A discussion about the use of formulas to estimate levothyroxine
[i]Causal relationship between thyroid dysfunction and hallux valgus[/i]
Hallux valgus is commonly referred to as a bunion.
The paper is complex - but the take-home is that there is a genetic relationship in at least some patients between hallux valgus and hypothyroidism.
Another one to add to the list...
[i]Causal relationship between thyroid dysfunction and hallux
Serum Thyrotropin and Triiodothyronine Levels in Levothyroxine-Treated Patients
Comment by Bianco:
[i]In LT4-treated patients (blue box=ref. FT4 range), the increase in FT4 is associated with a major drop in TSH, but the increase in blood T3 is minimal. LT4 is really good at normalizing TSH; not nearly as good at restoring T3, the active thyroid hormone.[/i]
I don't think
Plasma Metabolomics Reveals Systemic Metabolic Alterations of Subclinical and Clinical Hypothyroidism
This paper does what I have long been waiting for.
Takes some blood, just the serum, and do a comprehensive analysis of pretty much everything they can detect in that serum.
The subjects were divided into Control, Subclinical Hypothyroid and Hypothyroid groups.
They found clear differences