Experiences with

Olaparib

Olaparib for maintenance treatment of women with a mutation of their BRCA gene was withdrawn from the process and is therefore unavailable. It is important to note that these changes are to implemented in March, and that women currently on treatment will be able to complete the planned course.

Olaparib, as one example, has shown single-agent response rates ranging from 28% to 41%, depending on dose and BRCA status.

The trial compared the activity of the combination of the drug olaparib, which blocks DNA repair, and the blood vessel inhibitor drug cediranib, vs. olaparib alone.

During 2013, the company is planning to progress olaparib, intended as a maintenance treatment for platinum-sensitive relapsed ovarian cancer patients with BRCA mutations, onto Phase 3.

Also anyone had Olaparib or Topotecan Thanks for any responses.

as anyone heard of the drug trials olaparib... i know they have used them in the states but would like to know if anyone has tried it or heard abt it... is anyone on a drug trial.... how do u go about choosing a trial best wishes to u all shen x

The other thing that seems to be quoted is PARP inhibitors, specifically Olaparib. Is anything routinely offered, and does anyone have any experience of whether they work? Is there anything else? Should I be asking for anything at all, and if so, what?