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Rezvilutamide: new anti-androgen is better than Casodex added to ADT for newly diagnosed high-met HSPC. But is field too crowded?
Jiangsu Hengrui Medicine, a Chinese pharmaceutical manufacturer, published impressive results for its new drug Rezvilutamide. They randomized patients with 4 or more bone metastases to Rezvilutamide+ADT or Casodex+ADT. It increased 2-year radiographic progression-free survival by 56% and 2-year overall
Jiangsu Hengrui Medicine, a Chinese pharmaceutical manufacturer, published impressive results for its new drug Rezvilutamide. They randomized patients with 4 or more bone metastases to Rezvilutamide+ADT or Casodex+ADT. It increased 2-year radiographic progression-free survival by 56% and 2-year overall
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
Faslodex
Had a horrible reaction this past Monday after my injections. I’ve been having this treatment for 3 years and I had so much pain during the second injection. When I left I felt horrible. BP dropped to 78/56. I almost hit the deck. I experienced nausea, weakness, sweating and coworkers called 911 and
Had a horrible reaction this past Monday after my injections. I’ve been having this treatment for 3 years and I had so much pain during the second injection. When I left I felt horrible. BP dropped to 78/56. I almost hit the deck. I experienced nausea, weakness, sweating and coworkers called 911 and
Puppy_love
in
SHARE Metastatic Breast Cancer
2 years ago
Sick again
I had a UTI then the reaction to the new
Faslodex
and now I’m home sick with the worst cold ever. I don’t know if this is from stress or just my immune system saying quit your job. Anyone have this experience?
I had a UTI then the reaction to the new
Faslodex
and now I’m home sick with the worst cold ever. I don’t know if this is from stress or just my immune system saying quit your job. Anyone have this experience?
Puppy_love
in
SHARE Metastatic Breast Cancer
2 years ago
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SOC options have run out, PSMA negative, declining health - what's next?
My husband was diagnosed with high grade prostate cancer in 4/06 Gleason 4+3=7 in 12/12 cores with 90 to 100% involvement of the tissue cores. His original clinical staging was T2c versus T3. PSA at that time was 6.4. -First treatment was brachytherapy and IMRT. Undetectable PSA never reached. -Recurrance
My husband was diagnosed with high grade prostate cancer in 4/06 Gleason 4+3=7 in 12/12 cores with 90 to 100% involvement of the tissue cores. His original clinical staging was T2c versus T3. PSA at that time was 6.4. -First treatment was brachytherapy and IMRT. Undetectable PSA never reached. -Recurrance
Hidden
in
Advanced Prostate Cancer
2 years ago
tingling/numb fingers
After 18 months with daily 50mg bicalutamide mono therapy have tingling/numbness in pinky and ring finger of left hand. PSA remains below 0.1. Fingers work fine. It’s just irritating not debilitating. I read tingling is a listed Casodex side effect. Very reluctant to stop use because PSA remains very
After 18 months with daily 50mg bicalutamide mono therapy have tingling/numbness in pinky and ring finger of left hand. PSA remains below 0.1. Fingers work fine. It’s just irritating not debilitating. I read tingling is a listed Casodex side effect. Very reluctant to stop use because PSA remains very
kreg001
in
Advanced Prostate Cancer
2 years ago
Casodex 50mg
My husband is starting treatment again as his latest ct scan shows 2 positive pelvic lymph nodes, negative bone scan. He has started treatment and has been on Casodex for a month and had his first zolodex injection two days ago. Before the injection he started getting a rash on his neck today it
My husband is starting treatment again as his latest ct scan shows 2 positive pelvic lymph nodes, negative bone scan. He has started treatment and has been on Casodex for a month and had his first zolodex injection two days ago. Before the injection he started getting a rash on his neck today it
Knittingque
in
Advanced Prostate Cancer
2 years ago
Update
It was just a bad reaction to preservatives in the
faslodex
injection which was generic. He’s going to go back and order the
Faslodex
by Astra Zeneca which I had for the first two years and never had a problem.
It was just a bad reaction to preservatives in the
faslodex
injection which was generic. He’s going to go back and order the
Faslodex
by Astra Zeneca which I had for the first two years and never had a problem.
Ycats277
in
SHARE Metastatic Breast Cancer
2 years ago
DOES MEDICARE COVER DEXA SCANS FOR MEN WITH PROSTATE CANCER
I have been on Casodex and Eligard since June 2022. My PSA was still high after RALP so I had a GA-68 PSMA PET Scan done which revealed one 11mm tumor in the Left pelvic Lymph Nodes and one 7mm Tumor in the Right pelvic Lymph Nodes. Those were the only 2 hot spots in my body. My Dr. scheduled me for
I have been on Casodex and Eligard since June 2022. My PSA was still high after RALP so I had a GA-68 PSMA PET Scan done which revealed one 11mm tumor in the Left pelvic Lymph Nodes and one 7mm Tumor in the Right pelvic Lymph Nodes. Those were the only 2 hot spots in my body. My Dr. scheduled me for
GMan-62
in
Advanced Prostate Cancer
2 years ago
Verzenio causing pain in joins, taking a break and now NO the pain!
Im taking
Faslodex
, Zometa like you, my mets are throughout my spine. Diagnosed in 2019. Pleasepost a follow up if you can Blessings your way.😁
Im taking
Faslodex
, Zometa like you, my mets are throughout my spine. Diagnosed in 2019. Pleasepost a follow up if you can Blessings your way.😁
2019artist
in
SHARE Metastatic Breast Cancer
2 years ago
Continue Casodex or move to Lupron?
Hi guys, All the details are in my profile but the thumbnail is - RP 3 1/2 years ago with persistent PSA thus radiation and Lupron for a year. One year off, rising PSA at 1.6. Opted for monotherapy Casodex 50 mg. Two months later, PSA dropped to 0.5 so we stayed with it for another 6 months whereupon
Hi guys, All the details are in my profile but the thumbnail is - RP 3 1/2 years ago with persistent PSA thus radiation and Lupron for a year. One year off, rising PSA at 1.6. Opted for monotherapy Casodex 50 mg. Two months later, PSA dropped to 0.5 so we stayed with it for another 6 months whereupon
Bruce66
in
Advanced Prostate Cancer
2 years ago
New to the site and diagnosis
SUPER fit 66 year old. Only symptom was slow urine for past couple of years ( assumed due to age ). Take NO meds and have NO medical conditions. Went to for testosterone pellet for better daily gym weight lifting and running and had a PSA of 100. WTH? Then the journey started. MRI showed Pca and
SUPER fit 66 year old. Only symptom was slow urine for past couple of years ( assumed due to age ). Take NO meds and have NO medical conditions. Went to for testosterone pellet for better daily gym weight lifting and running and had a PSA of 100. WTH? Then the journey started. MRI showed Pca and
Hidden
in
Advanced Prostate Cancer
2 years ago
Latest Details on Approval of Oral SERDS - In Place of Faslodex Shots
Hi Fellow MBC’ers: Here is the latest I could find on the approval status of the long-awaited oral SERDs to replace those painful
Faslodex
shots: Patients with estrogen receptor–positive, HER2-negative advanced or metastatic breast cancer experienced a progression-free survival benefit after being treated
Hi Fellow MBC’ers: Here is the latest I could find on the approval status of the long-awaited oral SERDs to replace those painful
Faslodex
shots: Patients with estrogen receptor–positive, HER2-negative advanced or metastatic breast cancer experienced a progression-free survival benefit after being treated
hopenowandtomorrow
in
SHARE Metastatic Breast Cancer
2 years ago
Faslodex/Fulvestrant update
Faslodex
is my second line treatment- after Ibrance, Femara & zoladex. I’ve been feeling well on
Faslodex
- still going about my daily routine and working. After second MRI, my onc called with good news that there has been good shrinkage in liver and clavicle, and my femur had healed… yay!
Faslodex
is my second line treatment- after Ibrance, Femara & zoladex. I’ve been feeling well on
Faslodex
- still going about my daily routine and working. After second MRI, my onc called with good news that there has been good shrinkage in liver and clavicle, and my femur had healed… yay!
Ntash01
in
SHARE Metastatic Breast Cancer
2 years ago
Anyone Having to change to Verzenio
So we quickly changed from Ibrance/
faslodex
to Verzenio/ aromasin. Onc says she is trying to get more time( just 18 months so far) out of the CDK 4-6 class before the rear view window.
So we quickly changed from Ibrance/
faslodex
to Verzenio/ aromasin. Onc says she is trying to get more time( just 18 months so far) out of the CDK 4-6 class before the rear view window.
Bettybuckets
in
SHARE Metastatic Breast Cancer
2 years ago
No Evidence of Disease!!
Have been in Ibrance 125 and
Faslodex
since February 2021. My mets are in my liver only. I have been asymptomatic from the beginning (MBC found in scan for another issue). I see my oncologist monthly and like her very much. I have PET scans every 3 months. Brain MRI annually.
Have been in Ibrance 125 and
Faslodex
since February 2021. My mets are in my liver only. I have been asymptomatic from the beginning (MBC found in scan for another issue). I see my oncologist monthly and like her very much. I have PET scans every 3 months. Brain MRI annually.
1711JPD
in
SHARE Metastatic Breast Cancer
2 years ago
Is my Faslodex injection site a rash or shingles ? Has anyone had to stop because of severe rash ? What then , what replaces ? Help plz 🌹
4 years I’m taking the injections for
faslodex
. The injection site is always sore and the injections are painful . Has anyone had to stop due to this ? What did they put you on instead and is it working as well ? Scared 😱
4 years I’m taking the injections for
faslodex
. The injection site is always sore and the injections are painful . Has anyone had to stop due to this ? What did they put you on instead and is it working as well ? Scared 😱
Ycats277
in
SHARE Metastatic Breast Cancer
2 years ago
So afraid I won’t be able to take the faslodex injections anymore. Bad rash ! What then 😢
I’m so scared I’m just gonna die now from the cancer if I can’t take the
Faslodex
. Crying all the time. I don’t think it is shingles, I think it’s a hives rash . Going tomorrow as an emergency 🆘 to oncologist at 1 pm . Help
I’m so scared I’m just gonna die now from the cancer if I can’t take the
Faslodex
. Crying all the time. I don’t think it is shingles, I think it’s a hives rash . Going tomorrow as an emergency 🆘 to oncologist at 1 pm . Help
Ycats277
in
SHARE Metastatic Breast Cancer
2 years ago
Between a rock and another rock...
Was just told by my uro-onc that Casodex is about to kill me by shutting down my liver, based on 3 liver enzyme readings (ALT=177; AST=144; ALK.PH.=482). If I stop taking it, PCa will kill me. Right now, PSA is undetectable. Casodex monotherapy has worked for 4 yrs, but now I have very little choice
Was just told by my uro-onc that Casodex is about to kill me by shutting down my liver, based on 3 liver enzyme readings (ALT=177; AST=144; ALK.PH.=482). If I stop taking it, PCa will kill me. Right now, PSA is undetectable. Casodex monotherapy has worked for 4 yrs, but now I have very little choice
JPOM
in
Advanced Prostate Cancer
2 years ago
2nd opinion about treatment change?
So switched to Everolimus +
Faslodex
, which also gave a complete response for about 9 months. When the original breast tumour showed up again on a PET scan I was switched to Talazoparib, which I have felt very well on, much better than with the previous two lines of treatment.
So switched to Everolimus +
Faslodex
, which also gave a complete response for about 9 months. When the original breast tumour showed up again on a PET scan I was switched to Talazoparib, which I have felt very well on, much better than with the previous two lines of treatment.
Here_now
in
SHARE Metastatic Breast Cancer
2 years ago
Liver Mets - Ibrance - Tumor Markers
Well she was put on Ibrance/
Faslodex
and has been on it since. Her tumor markers were down to around 258. She has done great on it. She works full time and is just a fighter. We were given the impression she would not be here at Christmas so to be sitting here a year later is impressive!
Well she was put on Ibrance/
Faslodex
and has been on it since. Her tumor markers were down to around 258. She has done great on it. She works full time and is just a fighter. We were given the impression she would not be here at Christmas so to be sitting here a year later is impressive!
krismes
in
SHARE Metastatic Breast Cancer
2 years ago
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