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LU177
Since then he has had Casodex,
Enzalutamide
, R223, Docetaxel, Cabazitaxel and recently Abiraterone all of which have failed although
Enzalutamide
did work well for around 20 months.
Since then he has had Casodex,
Enzalutamide
, R223, Docetaxel, Cabazitaxel and recently Abiraterone all of which have failed although
Enzalutamide
did work well for around 20 months.
JanJames
in
Advanced Prostate Cancer
6 years ago
Rapid PSA, Failed Treatment.
I have had Lupron (7.5 yrs) Bicalutamide (1yr),
Enzalutamide
(2yrs), and Zytiga (2 months). It is the nature of my cancer to have a rapid PSA rise once a treatment has failed, however this is the fastest rise in my PSA.
I have had Lupron (7.5 yrs) Bicalutamide (1yr),
Enzalutamide
(2yrs), and Zytiga (2 months). It is the nature of my cancer to have a rapid PSA rise once a treatment has failed, however this is the fastest rise in my PSA.
GoEZ
in
Advanced Prostate Cancer
6 years ago
Low sugar with enzalutamide
My father has been on
enzalutamide
3 tablets daily for 5 months now. He has been on Eligard-45mg 6 monthly since May 2016. Chemo, radiation ,surgery , medical details mentioned in Bio. Recently started noticing low blood sugar levels for him, between 60-75 . It always had been around 110 earlier.
My father has been on
enzalutamide
3 tablets daily for 5 months now. He has been on Eligard-45mg 6 monthly since May 2016. Chemo, radiation ,surgery , medical details mentioned in Bio. Recently started noticing low blood sugar levels for him, between 60-75 . It always had been around 110 earlier.
caretkr
in
Advanced Prostate Cancer
6 years ago
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Xtandi [Enzalutamide ]. Continuation of ADT after CRPC & chemo.
Here, we analyzed the effect of concomitant ADT during
enzalutamide
treatment in men with mCRPC following chemotherapy.
Here, we analyzed the effect of concomitant ADT during
enzalutamide
treatment in men with mCRPC following chemotherapy.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
NUS researchers use AI to successfully treat metastatic cancer patient
This research is in the early stages, but it sounds promising: a new drug agent ZEN-3694 and
enzalutamide
have been used in combination to halt disease progression.
This research is in the early stages, but it sounds promising: a new drug agent ZEN-3694 and
enzalutamide
have been used in combination to halt disease progression.
curious-mind1
in
Advanced Prostate Cancer
6 years ago
BRCA ... Rubraca?
"The FDA has said that phase 2 data suggest the drug could represent a new therapy option for men whose cancer has progressed despite chemotherapy, and treatment with androgen receptor therapy such as Pfizer/Astellas’ Xtandi (
enzalutamide
), or Johnson & Johnson’s Zytiga (abiraterone)." https://pharmaphorum.com
"The FDA has said that phase 2 data suggest the drug could represent a new therapy option for men whose cancer has progressed despite chemotherapy, and treatment with androgen receptor therapy such as Pfizer/Astellas’ Xtandi (
enzalutamide
), or Johnson & Johnson’s Zytiga (abiraterone)." https://pharmaphorum.com
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Xtandi enzalutamide side effects dizzy/seizures
After having a dizzy spell while shopping at Costco to prep for the big weekend, my husband ended up in ER for most of Friday pre-Labor Day. What he experienced seemed to me like momentary seizure as earlier at Office Depot he had stared off into space and swayed sideways. No he is not having a reaction
After having a dizzy spell while shopping at Costco to prep for the big weekend, my husband ended up in ER for most of Friday pre-Labor Day. What he experienced seemed to me like momentary seizure as earlier at Office Depot he had stared off into space and swayed sideways. No he is not having a reaction
Grumpyswife
in
Advanced Prostate Cancer
6 years ago
A history of PSA readings, how accurate are they?
(PSMA PET Gallium scans showed bone metastasis in shoulders and lower back pre Lutetium treatment as well) From JULY 2018 PSA starting to rise again to 51 then started on
Enzalutamide
or Xtandi for 3 months to see if this would halt the rise .
(PSMA PET Gallium scans showed bone metastasis in shoulders and lower back pre Lutetium treatment as well) From JULY 2018 PSA starting to rise again to 51 then started on
Enzalutamide
or Xtandi for 3 months to see if this would halt the rise .
C0zm0cat
in
Advanced Prostate Cancer
6 years ago
A.I.-guided Chemo Halts Disease Worsening in Patient with mPRPC, Study Reports
Encouraging result after Zytiga (Abiraterone) failure from Phase1/2 Trial using Artificial Intelligence guided delivery of ZEN-3694 and Xtandi (
Enzalutamide
). http://prostatecancernewstoday.com/2018/09/13/artificial-intelligence-guided-chemo-halts-worsening-metastatic-prostate-cancer-patient/
Encouraging result after Zytiga (Abiraterone) failure from Phase1/2 Trial using Artificial Intelligence guided delivery of ZEN-3694 and Xtandi (
Enzalutamide
). http://prostatecancernewstoday.com/2018/09/13/artificial-intelligence-guided-chemo-halts-worsening-metastatic-prostate-cancer-patient/
Moespy
in
Advanced Prostate Cancer
6 years ago
Cholesterol biosynthesis & Enzalutamide resistance
"Although patients can benefit from
enzalutamide
at the beginning of ... therapy, acquired
enzalutamide
resistance usually occurs within a short period."
"Although patients can benefit from
enzalutamide
at the beginning of ... therapy, acquired
enzalutamide
resistance usually occurs within a short period."
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Pain in the Prostate (worse after TURP)
My previous MO said I had to stay on Zoladex as well as
Enzalutamide
. I'm not sure which one is right. Does anyone have any thoughts?
My previous MO said I had to stay on Zoladex as well as
Enzalutamide
. I'm not sure which one is right. Does anyone have any thoughts?
paulofaus
in
Advanced Prostate Cancer
6 years ago
Hormone refractory/ castrate resistant
If you respond to Zytiga/
Enzalutamide
are you still considered hormone sensitive? I assumed my husband was hormone refractory once his PSA started rising on Lupron/ Casodex combo. It’s still to be determined if he will respond to the
Enzalutamide
.
If you respond to Zytiga/
Enzalutamide
are you still considered hormone sensitive? I assumed my husband was hormone refractory once his PSA started rising on Lupron/ Casodex combo. It’s still to be determined if he will respond to the
Enzalutamide
.
Blair77
in
Advanced Prostate Cancer
6 years ago
Deciding on Chemo or alternatives ?
I have read that if you have a negative ARV7 test that
Enzalutamide
might still work. If I have a negative ARV7 then perhaps I could get a few months from
Enzalutamide
before starting Chemo. Can anyone comment on that sequencing strategy? My doc seems to be pushing me toward Chemo.
I have read that if you have a negative ARV7 test that
Enzalutamide
might still work. If I have a negative ARV7 then perhaps I could get a few months from
Enzalutamide
before starting Chemo. Can anyone comment on that sequencing strategy? My doc seems to be pushing me toward Chemo.
CarlinPhoenix
in
Advanced Prostate Cancer
6 years ago
Enzalutamide is sapping my energy and spirit
Been on this drug for 4 months and PSA is still rising past 100 (at much slower rate though). I also hate how I feel on it - really yucky, super fatigued and brain fogged (nasal blockage issues too). All this only really started in the past 6 weeks or so. Also finding exercise extremely difficult - steady
Been on this drug for 4 months and PSA is still rising past 100 (at much slower rate though). I also hate how I feel on it - really yucky, super fatigued and brain fogged (nasal blockage issues too). All this only really started in the past 6 weeks or so. Also finding exercise extremely difficult - steady
Sriyantra
in
Advanced Prostate Cancer
6 years ago
Starting Abiraterone/Pedizisone
Two things have happened since I stopped
Enzalutamide
. I was told to stop taking
Enzalutamide
on Tuesday because they were going to overnight Abiraterone/Pedizisone. Didn’t happen as planned, didn’t start new treatment till Friday. However, the pain in my shoulders, hands, and arms has subsided.
Two things have happened since I stopped
Enzalutamide
. I was told to stop taking
Enzalutamide
on Tuesday because they were going to overnight Abiraterone/Pedizisone. Didn’t happen as planned, didn’t start new treatment till Friday. However, the pain in my shoulders, hands, and arms has subsided.
GoEZ
in
Advanced Prostate Cancer
6 years ago
"Radium-223 (Xofigo) with concurrent abiraterone or enzalutamide: predictive biomarkers of improved overall survival ...
Baseline pain and ECOG PS as well as concurrent usage of abiraterone or
enzalutamide
were recorded. Side effect profiles for each patient throughout treatment were noted.
Baseline pain and ECOG PS as well as concurrent usage of abiraterone or
enzalutamide
were recorded. Side effect profiles for each patient throughout treatment were noted.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Activity and Safety of Enzalutamide in Patients with mCRPC Previously Treated with Abiraterone Acetate Plus Prednisone for ≥24 weeks.
The prospective data herein show the antitumour activity of
enzalutamide
in patients who progressed following ≥24 wk of abiraterone and support the use of
enzalutamide
in some patients in the postabiraterone setting.
The prospective data herein show the antitumour activity of
enzalutamide
in patients who progressed following ≥24 wk of abiraterone and support the use of
enzalutamide
in some patients in the postabiraterone setting.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
New to site.
I am presently have a rising PSA on
Enzalutamide
and will be going on Abiraterone/Pedizisone pills. I guess I need a place to vent with people who understand. My family support has been great. They have been there for me with all the ups and downs.
I am presently have a rising PSA on
Enzalutamide
and will be going on Abiraterone/Pedizisone pills. I guess I need a place to vent with people who understand. My family support has been great. They have been there for me with all the ups and downs.
GoEZ
in
Advanced Prostate Cancer
6 years ago
Metastasis-free Survival - Enzalutamide.
In the same issue of the NEJM, we have: "
Enzalutamide
in Men with Nonmetastatic, Castration-Resistant Prostate Cancer" [2].
In the same issue of the NEJM, we have: "
Enzalutamide
in Men with Nonmetastatic, Castration-Resistant Prostate Cancer" [2].
pjoshea13
in
Advanced Prostate Cancer
6 years ago
TURP and Enzalutamide advice
I'm on
Enzalutamide
now (plus Lupron since Oct) but not responding very much after almost 3 months 😔.
I'm on
Enzalutamide
now (plus Lupron since Oct) but not responding very much after almost 3 months 😔.
Sriyantra
in
Advanced Prostate Cancer
6 years ago
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