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Docetaxel
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Chemo One More Time
Tomorrow I will start my 4th round of chemo with
Docetaxel
/Carboplatin combo. Since September 2017, I have had 16 infusions (2 rounds of 6 cycles and most recent round of 4 cycles) of this same treatment, with rechallenges of Xtandi in between.
Tomorrow I will start my 4th round of chemo with
Docetaxel
/Carboplatin combo. Since September 2017, I have had 16 infusions (2 rounds of 6 cycles and most recent round of 4 cycles) of this same treatment, with rechallenges of Xtandi in between.
vandy69
in
Advanced Prostate Cancer
5 years ago
Update on my 83 year old best friend and questions
Not accepted to study so started 8/18 /19 on
Docetaxel
with dexamethosome every 3 weeks and completed 6 sessions . Last chemo was December 4, 2019. No more chemo as there was considerable edema on limbs and pink eye. MO suggested Radium 223 for next treatment.
Not accepted to study so started 8/18 /19 on
Docetaxel
with dexamethosome every 3 weeks and completed 6 sessions . Last chemo was December 4, 2019. No more chemo as there was considerable edema on limbs and pink eye. MO suggested Radium 223 for next treatment.
Hidden
in
Advanced Prostate Cancer
5 years ago
Testosterone & Docetaxel in CRPC.
Abstract BACKGROUND: The role of testosterone as a prognostic factor for castration-resistant prostate cancer treated with
docetaxel
in Japan was investigated.
Abstract BACKGROUND: The role of testosterone as a prognostic factor for castration-resistant prostate cancer treated with
docetaxel
in Japan was investigated.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
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Docetaxel 6 cycles, should it be extended to 10 cycles?
Currently, dad is in his 5th cycle. With each cycle ALP and PSA continue to fall, the lowest being the current one. (PSA = 0.07, ALP = 143 ) || MHSPC with widespread Bone Mets. Original PSA 143 to 1.43, ALP 887 to 443 with Firmagon, then started chemo || - PSA trend during chemo: 0.311 -> 0.252
Currently, dad is in his 5th cycle. With each cycle ALP and PSA continue to fall, the lowest being the current one. (PSA = 0.07, ALP = 143 ) || MHSPC with widespread Bone Mets. Original PSA 143 to 1.43, ALP 887 to 443 with Firmagon, then started chemo || - PSA trend during chemo: 0.311 -> 0.252
Cheerr
in
Advanced Prostate Cancer
5 years ago
STREAM. Enzalutamide + ADT with Salvage Radiation in high-risk PSA-recurrent PCa after RP
[u]in a trial of men with similar eligibility treated with salvage RT and adjuvant
docetaxel
[/u]." "The 3-yr {progression-free survival} was 53%."
[u]in a trial of men with similar eligibility treated with salvage RT and adjuvant
docetaxel
[/u]." "The 3-yr {progression-free survival} was 53%."
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Pembrolizumab for Treatment-Refractory Metastatic Castration-Resistant Prostate Cancer
CONCLUSION Pembrolizumab monotherapy shows antitumor activity with an acceptable safety profile in a subset of patients with RECIST-measurable and bone-predominant mCRPC previously treated with
docetaxel
and targeted endocrine therapy.
CONCLUSION Pembrolizumab monotherapy shows antitumor activity with an acceptable safety profile in a subset of patients with RECIST-measurable and bone-predominant mCRPC previously treated with
docetaxel
and targeted endocrine therapy.
Balsam01
in
Advanced Prostate Cancer
5 years ago
When to move on to next treatment?
Husband diagnosed 8/2017, PSA 556, bone marrow, bone and lymph node involvement, 10 rounds
docetaxel
, 2 months off before PSA started to rise. Started xtandi and got to nadir of .78 then in April of this year
docetaxel
re-challenge when PSA rose over 6.
Husband diagnosed 8/2017, PSA 556, bone marrow, bone and lymph node involvement, 10 rounds
docetaxel
, 2 months off before PSA started to rise. Started xtandi and got to nadir of .78 then in April of this year
docetaxel
re-challenge when PSA rose over 6.
joekaty
in
Advanced Prostate Cancer
5 years ago
Lupron and Heart Issues
He was treated with the new protocol at the time-6 cycles of
docetaxel
, radiation and lupron every 6 months. He has responded very well cancer wise but has developed heart problems, having 4 Non STEMI heart attacks—always in the spring(!) for the past 4 years. He has wonderful specialists.
He was treated with the new protocol at the time-6 cycles of
docetaxel
, radiation and lupron every 6 months. He has responded very well cancer wise but has developed heart problems, having 4 Non STEMI heart attacks—always in the spring(!) for the past 4 years. He has wonderful specialists.
Snowbird1
in
Advanced Prostate Cancer
5 years ago
Concerned -- Husband's PSA Doubled 4 to 8 between 4th and 5th Chemo Treatment
Husband Barry's PSA doubled from 4 to 8 between his 4th and 5th of six scheduled chemo (
Docetaxel
) treatments. It had dropped from 6 to 4 after first chemo treatment, and stayed at 4 during the next 3 treatments.
Husband Barry's PSA doubled from 4 to 8 between his 4th and 5th of six scheduled chemo (
Docetaxel
) treatments. It had dropped from 6 to 4 after first chemo treatment, and stayed at 4 during the next 3 treatments.
Barbara345
in
Advanced Prostate Cancer
5 years ago
docetaxel side effects
Hello - just finished my 3rd infusion of
docetaxel
and it's starting to take a hit on me, more then the first two - has anyone experienced: Flu-like symptoms Face flushing and heating up - just the face Sinus headache, and a slight nose bleed MO has my PSA down to 0.43 from what he claims from 300
Hello - just finished my 3rd infusion of
docetaxel
and it's starting to take a hit on me, more then the first two - has anyone experienced: Flu-like symptoms Face flushing and heating up - just the face Sinus headache, and a slight nose bleed MO has my PSA down to 0.43 from what he claims from 300
ken12491
in
Advanced Prostate Cancer
5 years ago
Survival With Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer in Clinical Practice
– Neil Majithia, MD BACKGROUND Cabazitaxel is a treatment of metastatic castration-resistant prostate cancer (mCRPC) after
docetaxel
failure.
– Neil Majithia, MD BACKGROUND Cabazitaxel is a treatment of metastatic castration-resistant prostate cancer (mCRPC) after
docetaxel
failure.
Balsam01
in
Advanced Prostate Cancer
5 years ago
Oligometastatic PC and Radiation
We have been advised by the medical oncologist that the next step is either
Docetaxel
chemotherapy or Zytiga. Meanwhile, my husband went to a PC conference out of town recently.
We have been advised by the medical oncologist that the next step is either
Docetaxel
chemotherapy or Zytiga. Meanwhile, my husband went to a PC conference out of town recently.
Dett
in
Advanced Prostate Cancer
5 years ago
Could Use Some Advice As Change May Be Afoot
Docetaxel
? LU-177? Something else? Exceot for the PC, I am other wise healthy except for some orthopedic issues) and only 61. No heart issues. One other thing- I just started getting some neuropathy in my left leg, mostly in my shin area. Any suggestions to improve that would also be appreciated.
Docetaxel
? LU-177? Something else? Exceot for the PC, I am other wise healthy except for some orthopedic issues) and only 61. No heart issues. One other thing- I just started getting some neuropathy in my left leg, mostly in my shin area. Any suggestions to improve that would also be appreciated.
jfoesq
in
Advanced Prostate Cancer
5 years ago
Docetaxel not working, fractured hip and pelvis
They recommend not giving up on
docetaxel
, but combining the 2 treatments as they have experience with the combo treatment working. Anyone tried that? Also, my local academic med center in NH will not do surgery on my hip/pelvis until I am finished with carboplatin due to risk of infection.
They recommend not giving up on
docetaxel
, but combining the 2 treatments as they have experience with the combo treatment working. Anyone tried that? Also, my local academic med center in NH will not do surgery on my hip/pelvis until I am finished with carboplatin due to risk of infection.
robbo262
in
Advanced Prostate Cancer
5 years ago
Pseudoprogression.
DESIGN, SETTING, AND PARTICIPANTS: This post hoc, retrospective secondary analysis of 1672 enzalutamide-treated men from 2 phase 3, randomized mCRPC studies (PREVAIL and AFFIRM) before or after treatment with
docetaxel
was conducted from April 12, 2018, to July 25, 2019.
DESIGN, SETTING, AND PARTICIPANTS: This post hoc, retrospective secondary analysis of 1672 enzalutamide-treated men from 2 phase 3, randomized mCRPC studies (PREVAIL and AFFIRM) before or after treatment with
docetaxel
was conducted from April 12, 2018, to July 25, 2019.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Enzamet
Underwent ADT + Lupron + 6 rounds of
docetaxel
. PSA nadir 0.01. Currently hovering around 0.01-0.02. Our oncologist and I had previously discussed potentially adding abiraterone shortly after chemotherapy (never did start it though).
Underwent ADT + Lupron + 6 rounds of
docetaxel
. PSA nadir 0.01. Currently hovering around 0.01-0.02. Our oncologist and I had previously discussed potentially adding abiraterone shortly after chemotherapy (never did start it though).
mediocra
in
Advanced Prostate Cancer
5 years ago
Results after 5th Docetaxel infusion and just started 6th
He believed the results will show improvement vs the scan I did in April. 3) As indicated in the last posting, Onco suggested that once done with the 6th infusion of
docetaxel
, and the results continue to show progress, he is suggesting I will only need to Lucrin and Zometa.
He believed the results will show improvement vs the scan I did in April. 3) As indicated in the last posting, Onco suggested that once done with the 6th infusion of
docetaxel
, and the results continue to show progress, he is suggesting I will only need to Lucrin and Zometa.
bellyhappy58
in
Advanced Prostate Cancer
5 years ago
Veyonda (idronoxil). For enhancing radiation effects and launching abscopal immune response. DARRT Trials and LuPIN Trial
LuPIN-1 trial of Veyonda with Lu-PSMA-617 in mCRPC (Australia) LuPIN-1 is a dose escalation and dose expansion trial of men with mCRPC progressing despite having received
docetaxel
, cabazitaxel and either abiraterone or enzalutamide.
LuPIN-1 trial of Veyonda with Lu-PSMA-617 in mCRPC (Australia) LuPIN-1 is a dose escalation and dose expansion trial of men with mCRPC progressing despite having received
docetaxel
, cabazitaxel and either abiraterone or enzalutamide.
MateoBeach
in
Advanced Prostate Cancer
5 years ago
docetaxel and Luekine
Just finished my second shot of
docetaxel
- did ok... My WBC was low on the injection so the Dr added daily injections of Luekine to boost WBC ( I do at home ) --- the combo has taken a pretty hard hit on me. Loss of appetite - taste buds are gone - fatigued.
Just finished my second shot of
docetaxel
- did ok... My WBC was low on the injection so the Dr added daily injections of Luekine to boost WBC ( I do at home ) --- the combo has taken a pretty hard hit on me. Loss of appetite - taste buds are gone - fatigued.
ken12491
in
Advanced Prostate Cancer
5 years ago
2019 Top Stories in Advanced Prostate Cancer: Cabazitaxel vs Abiraterone or Enzalutamide in Metastatic Prostate Cancer
Based on this study in patients who have progressed on both
docetaxel
and an androgen signaling–targeted inhibitor, the better option for next-line therapy would be cabazitaxel over the other androgen signaling–targeted inhibitor.
Based on this study in patients who have progressed on both
docetaxel
and an androgen signaling–targeted inhibitor, the better option for next-line therapy would be cabazitaxel over the other androgen signaling–targeted inhibitor.
Balsam01
in
Advanced Prostate Cancer
5 years ago
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