Therapies Targeted to Androgen Receptor SignalingAxis in Prostate Cancer: Progress, Challenges,and Hope - published December 2019
impedes
the androgen synthesis. [120]
Glycyrrhetinic acid Targets 17,20-lyase enzyme and thus decreases the testosterone level. [121]
Curcumin Curcumin analogs function as androgen antagonists, inhibit testosterone-, DHT-induced AR activity. [122]
Niphatenones The glycerol ethers from the sponge Niphates digitalis
impedes
the androgen synthesis. [120]
Glycyrrhetinic acid Targets 17,20-lyase enzyme and thus decreases the testosterone level. [121]
Curcumin Curcumin analogs function as androgen antagonists, inhibit testosterone-, DHT-induced AR activity. [122]
Niphatenones The glycerol ethers from the sponge Niphates digitalis