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Degarelix
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Chemo failure. What next?
Since diagnosis last September have monthly
Degarelix
injections. Chemo was stopped. Oncologist phoned to say he was happy with PSA and to come back in 3 months. Covid means they don't won't face to face appointments. After the chest infection, I can hardly walk.
Since diagnosis last September have monthly
Degarelix
injections. Chemo was stopped. Oncologist phoned to say he was happy with PSA and to come back in 3 months. Covid means they don't won't face to face appointments. After the chest infection, I can hardly walk.
skulleryman
in
Advanced Prostate Cancer
4 years ago
Any news on estrogen patches or gel in comparison to lupron or degarelix regarding cardiovascular problems, blood clots?
My husband will probably begin ADT but still concerned about cardiovascular issues, specially blood clots. What about estrogen patches or gel, any news?
My husband will probably begin ADT but still concerned about cardiovascular issues, specially blood clots. What about estrogen patches or gel, any news?
Hidden
in
Advanced Prostate Cancer
4 years ago
Decision Matrix Conundrum
Used adjuvant ADT with
degarelix
plus estradiol patches. Approximately 5-6 months until T levels recovered. Post RT my PSA fell by about half (.25 to .15 and staying there for 3 months now).
Used adjuvant ADT with
degarelix
plus estradiol patches. Approximately 5-6 months until T levels recovered. Post RT my PSA fell by about half (.25 to .15 and staying there for 3 months now).
MateoBeach
in
Advanced Prostate Cancer
4 years ago
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Fenbendazole probably not working for me
PSA returned, 3.65, with cessation of ADT, so recommenced
degarelix
Dec 2015 (I had waited a couple of months while expecting to start Dr. Amato’s trial of apalutamide, which never did start due to his health and eventual death.)
PSA returned, 3.65, with cessation of ADT, so recommenced
degarelix
Dec 2015 (I had waited a couple of months while expecting to start Dr. Amato’s trial of apalutamide, which never did start due to his health and eventual death.)
cigafred
in
Advanced Prostate Cancer
4 years ago
Completed Trial Treatment (NCT02849990) Degarelix (Firmagon) and Apalutamide (Erleada) orally for 12 months.
Hi All, I finished the trial two weeks ago. PSA is still undetectable @ 0.06. MO recommended Lupron shot every three months as standard treatment. Starting Lupron shot this Friday and wondering what l am in for? Can someone please share the effects of Lupron short or Is this the standard treatment
Hi All, I finished the trial two weeks ago. PSA is still undetectable @ 0.06. MO recommended Lupron shot every three months as standard treatment. Starting Lupron shot this Friday and wondering what l am in for? Can someone please share the effects of Lupron short or Is this the standard treatment
Bab63
in
Advanced Prostate Cancer
4 years ago
Is There Still a Role for Bilateral Orchidectomy in ADT for Metastatic Prostate Cancer?
Recent Egyption study [1] comparing physical castration to
Degarelix
[Firmagon]. (
Degarelix
is a GnRH [LHRH] [u]antagonist[/u]. Traditional chemical castration drugs such as Lupron are GnRH receptor agonists.)
Recent Egyption study [1] comparing physical castration to
Degarelix
[Firmagon]. (
Degarelix
is a GnRH [LHRH] [u]antagonist[/u]. Traditional chemical castration drugs such as Lupron are GnRH receptor agonists.)
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Medical bill for hormone treatment
I am getting
Degarelix
and Xgeva injections. The doctor's office sent me a bill amounting $2600 which is the deductible from Anthem blue cross. I am covered at the same time by Medicare. It seems I have to pay only 20 per cent of the $2600. But they insists I am responsible for the amount.
I am getting
Degarelix
and Xgeva injections. The doctor's office sent me a bill amounting $2600 which is the deductible from Anthem blue cross. I am covered at the same time by Medicare. It seems I have to pay only 20 per cent of the $2600. But they insists I am responsible for the amount.
pigpiggy2633
in
Advanced Prostate Cancer
4 years ago
Surgical Castration. Why is it uncommon?
It is consistant with what is now reported for
degarelix
. The issues also gets raised about the irreversibility of a surgical castration.
It is consistant with what is now reported for
degarelix
. The issues also gets raised about the irreversibility of a surgical castration.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Degarelix 240mg , as the first treatments??
Today he got his first shot ,
Degarelix
240mg , the urologist said we should wait for the result in a month, he said for now , we can’t tell which treatment may come next! I googled the name and I found out it’s a chemotherapy medication, what does it mean to you ?
Today he got his first shot ,
Degarelix
240mg , the urologist said we should wait for the result in a month, he said for now , we can’t tell which treatment may come next! I googled the name and I found out it’s a chemotherapy medication, what does it mean to you ?
Seabird12
in
Advanced Prostate Cancer
4 years ago
Side effects of degarelix
I was having side effect taking
degarelix
what with weakness, area swelling, fever but I was tollerating it. Dr. said I could get the three month shot. What one almost killed me. the time release was litterially an ovedose. Went back to the once a month.
I was having side effect taking
degarelix
what with weakness, area swelling, fever but I was tollerating it. Dr. said I could get the three month shot. What one almost killed me. the time release was litterially an ovedose. Went back to the once a month.
Peepers
in
Advanced Prostate Cancer
4 years ago
Non standard Firmagon dosing effective for 3 months from single injection.
The initial dose half-life of
degarelix
is 40 days due to slow release of drug from depot in fat tissue. I will update this with the 4 month post-injection results in February 2020.
The initial dose half-life of
degarelix
is 40 days due to slow release of drug from depot in fat tissue. I will update this with the 4 month post-injection results in February 2020.
MateoBeach
in
Advanced Prostate Cancer
4 years ago
Bone Marrow Involvement?
He has now had 3 months of
degarelix
and 1.5 months of Zytiga/prednisone PSA is down to 11. However his hemoglobin has dropped to 10.8 and is RBC is low and 3.68. Furthermore, his Myelocyte Absolute Manual and Automated nRBC Absolute are all a bit high.
He has now had 3 months of
degarelix
and 1.5 months of Zytiga/prednisone PSA is down to 11. However his hemoglobin has dropped to 10.8 and is RBC is low and 3.68. Furthermore, his Myelocyte Absolute Manual and Automated nRBC Absolute are all a bit high.
j5000
in
Advanced Prostate Cancer
5 years ago
ore details on degarelix (Firmagon)
Conversely, leuprolide had a seemingly more favorable effect on insomnia and bodily pain than
degarelix
; however, the mean increase in insomnia with
degarelix
may be explained in part by significantly lower baseline insomnia in this group.
Conversely, leuprolide had a seemingly more favorable effect on insomnia and bodily pain than
degarelix
; however, the mean increase in insomnia with
degarelix
may be explained in part by significantly lower baseline insomnia in this group.
MateoBeach
in
Advanced Prostate Cancer
5 years ago
Cardiovascular Disease & ADT.
CONCLUSIONS: There were increased risks of cardiovascular disease with use of GnRH agonists and
degarelix
, but not with bicalutamide monotherapy.
CONCLUSIONS: There were increased risks of cardiovascular disease with use of GnRH agonists and
degarelix
, but not with bicalutamide monotherapy.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Leuprolide: Eligard VS Lupron (1 month, 3 month, 6 months)
============== Also: What about Firmagon (
degarelix
). I understand that it is an antagonist whereas Eligard and Lupron are agonists? Is that so? That doesn't sound so right to me?
============== Also: What about Firmagon (
degarelix
). I understand that it is an antagonist whereas Eligard and Lupron are agonists? Is that so? That doesn't sound so right to me?
cesanon
in
Advanced Prostate Cancer
5 years ago
Fenbendazole Just Might be Working–Part 1
6/17/15<0.01Resulting PSAAs the
degarelix
wore off, PSA returned 12/22/163.64re-started
degarelix
6/8/170.02PSA reached on 6/8/17 Continued at exactly 0.02 for 22 measurements until 8/6/19 8/20/180.02Switched from
degarelix
to lupron due to side effects 6/4/19Started Fenbendazole, one week constant
6/17/15<0.01Resulting PSAAs the
degarelix
wore off, PSA returned 12/22/163.64re-started
degarelix
6/8/170.02PSA reached on 6/8/17 Continued at exactly 0.02 for 22 measurements until 8/6/19 8/20/180.02Switched from
degarelix
to lupron due to side effects 6/4/19Started Fenbendazole, one week constant
cigafred
in
Advanced Prostate Cancer
5 years ago
Celebrating with a visit for Canadian Ducoral
ON Monday I will start on
Degarelix
, (my bicalutamide with dutasteride regimen failing after 4+ years.) I'll probably keep the dutasteride as it keeps adrenal androgens from being metabolized to the most active form. (DHT) Wondering if estradiol would be a good addition at this time.
ON Monday I will start on
Degarelix
, (my bicalutamide with dutasteride regimen failing after 4+ years.) I'll probably keep the dutasteride as it keeps adrenal androgens from being metabolized to the most active form. (DHT) Wondering if estradiol would be a good addition at this time.
MateoBeach
in
Advanced Prostate Cancer
5 years ago
Long Overdue Update
Degarelix
and Casodex tried first. First dose of docetaxel started in ICU and he survived to be discharged, wasn’t expected to live six months. 9 rounds of docetaxel, taken off my MD Anderson. Nadir was 2.28 I believe. Two months later PSA rising again and Xtandi started.
Degarelix
and Casodex tried first. First dose of docetaxel started in ICU and he survived to be discharged, wasn’t expected to live six months. 9 rounds of docetaxel, taken off my MD Anderson. Nadir was 2.28 I believe. Two months later PSA rising again and Xtandi started.
joekaty
in
Advanced Prostate Cancer
5 years ago
I'm new here and just finished clinical trial.
I have done a 1 year trial of
Degarelix
injections. My MO has me at stage 4 metastatic prostate cancer. If it progresses much further, I am thinking of retiring early at age 58 because the Andregan Depletion Therapy is kicking my butt!
I have done a 1 year trial of
Degarelix
injections. My MO has me at stage 4 metastatic prostate cancer. If it progresses much further, I am thinking of retiring early at age 58 because the Andregan Depletion Therapy is kicking my butt!
farm15
in
Advanced Prostate Cancer
5 years ago
Firmagon (Degarelix) my first injection...
Any one here has Firmagon (
Degarelix
) treatment information regarding the supplements and vitamins that can interfere with the efficiency of this treatment?? I got 240 mg in my abdomen 2 sites subcutaneously, with some redness and pain in the area.
Any one here has Firmagon (
Degarelix
) treatment information regarding the supplements and vitamins that can interfere with the efficiency of this treatment?? I got 240 mg in my abdomen 2 sites subcutaneously, with some redness and pain in the area.
Ralph1966
in
Advanced Prostate Cancer
5 years ago
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