Experiences with

Daunorubicin

- Induction chemotherapy with cytarabine and daunorubicin. - Initially, non-itchy skin lesion on left forearm. Later, lesions developed on the neck and venipuncture sites (site of a vein where blood is taken). The latter was pathergy - skin lesions develop where the skin has been damaged.

For the first chemo, she is administered with daunorubicin instead of docetaxel. Is this okay?

Daily treatment of prostate cancer xenograft-bearing mice with low-dose anthracycline (doxorubicin or daunorubicin) chemotherapy inhibits HIF-1 DNA-binding activity, HIF-1-dependent expression of angiogenic growth factors, mobilization of circulating angiogenic cells, and tumor vascularization, thereby

THEN: Childhood leukemia survivor - rare Acute Monocytic Leukemia (2 years old, now 39), Treatment: Extreme spinal/cranial radiation (52GY) & Chemotherapy Enrolled in human growth hormone program NOW: Chemotherapy drug - Daunorubicin (overdose) induced dilated cardiomyopathy Hypothyroidism (Thyroid

Mention is also made of the drugs doxorubicin and daunorubicin, which come from a bacteria originally found in the ground outside a 13th century Italian castle, along with vinblastine and vincristine, which were originally extracted from the Madagascar periwinkle plant.