Experiences with
Auranofin

2 public posts

dopamine precursors, SuperDopa and SuperDopAmid as potential neuroprotective agents for slowing Parkinsons

, an organo-gold compound that inhibits thioredoxin-reductase activity and elevates ROS in the cell Increasing concentration of SD1 inhibits p38MAPK and ERK1/2 activity acting through the reversal of auranofin oxidizing effects in human neuronal SH-SY5Y cells SD1 can also cross the blood brain barrier

, an organo-gold compound that inhibits thioredoxin-reductase activity and elevates ROS in the cell Increasing concentration of SD1 inhibits p38MAPK and ERK1/2 activity acting through the reversal of auranofin oxidizing effects in human neuronal SH-SY5Y cells SD1 can also cross the blood brain barrier

in Cure Parkinson's

3 years ago

The thyroid hormone converting enzyme human deiodinase 1 is inhibited by gold ions from inorganic salts, organic substances, ...

The three organic gold substances aurothioglucose, auranofin and sodium aurothiomalate inhibited DIO1 with IC50 between 0.38 and 0.75 μM while their structural analogues lacking the gold ion did not.

The three organic gold substances aurothioglucose, auranofin and sodium aurothiomalate inhibited DIO1 with IC50 between 0.38 and 0.75 μM while their structural analogues lacking the gold ion did not.

Thyroid UKin Thyroid UK

3 years ago

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