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Decision made, approval received. Will be starting Acalabrutinib at NIH
I am hoping that the
Acalabrutinib
will knock things back enough to buy me time until they get the combos further along. Thanks your for all your support, recommendations, kind words, etc.
I am hoping that the
Acalabrutinib
will knock things back enough to buy me time until they get the combos further along. Thanks your for all your support, recommendations, kind words, etc.
SandiC
in
CLL Support
8 years ago
What to do?
Acalabrutinib
clinical trial at NIH - easy peasy and no cost at all. But I would have to stay on acalabrutib until I relapse/resist/etc.; or 2. Triple clinical trial at OSU (Byrd) for obinutuzimab, Ibrutinib and Venetoclax for 14 months.
Acalabrutinib
clinical trial at NIH - easy peasy and no cost at all. But I would have to stay on acalabrutib until I relapse/resist/etc.; or 2. Triple clinical trial at OSU (Byrd) for obinutuzimab, Ibrutinib and Venetoclax for 14 months.
SandiC
in
CLL Support
8 years ago
Dr Susan O'Brien Sheds Light on Role of Next-Generation Agents in CLL
[/i] OncLive interview with Dr O'Brien: http://global.onclive.com/web-exclusives/expert-sheds-light-on-role-of-nextgeneration-agents-in-cll Drugs mentioned: ibrutinib (Imbruvica) idelalisib (Zydelig) duvelisib in trial versus ofatumumab (Arzerra) TGR-1202 (PI3K inhibitor)
acalabrutinib
, (ACP-196) a
[/i] OncLive interview with Dr O'Brien: http://global.onclive.com/web-exclusives/expert-sheds-light-on-role-of-nextgeneration-agents-in-cll Drugs mentioned: ibrutinib (Imbruvica) idelalisib (Zydelig) duvelisib in trial versus ofatumumab (Arzerra) TGR-1202 (PI3K inhibitor)
acalabrutinib
, (ACP-196) a
AussieNeil
Administrator
in
CLL Support
8 years ago
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Dr Sharman's inaugural guest blog on Venclexta / Venetoclax / ABT-199, by Tom Boyd; Essential reading if you are considering this treatment
Considering treatment with Venclexta (or its myriad names) or Ibrurinib (and its myriad names) or ACP196/
acalabrutinib
(and I'm sure it will soon gain another name)?
Considering treatment with Venclexta (or its myriad names) or Ibrurinib (and its myriad names) or ACP196/
acalabrutinib
(and I'm sure it will soon gain another name)?
AussieNeil
Administrator
in
CLL Support
8 years ago
ACP-196 (BTK inhibitor acalabrutinib) Trial
Well, my husband is now at the 12 month point on this trial. Bloods etc are all OK. He had a bone marrow biopsy while we were at Kings last Monday and will find out the results on our next 3 month visit in June. Judging on the results of one of the patients who is three months ahead of us on the trial
Well, my husband is now at the 12 month point on this trial. Bloods etc are all OK. He had a bone marrow biopsy while we were at Kings last Monday and will find out the results on our next 3 month visit in June. Judging on the results of one of the patients who is three months ahead of us on the trial
babswade
in
CLL Support
8 years ago
Have Johnson & Johnson and AstraZeneca done one better than AbbVie, purchasing 55 percent of Acerta Pharma for acalabrutinib (ACP-196)?
[i]"Earlier this year, AbbVie won an intense bidding war for Pharmacyclics, paying $21 billion for the company and the right to split sales of its potential blockbuster blood-cancer drug Imbruvica with Johnson & Johnson. AstraZeneca may have just done AbbVie one better."[/i] http://www.chicagobusiness.com
[i]"Earlier this year, AbbVie won an intense bidding war for Pharmacyclics, paying $21 billion for the company and the right to split sales of its potential blockbuster blood-cancer drug Imbruvica with Johnson & Johnson. AstraZeneca may have just done AbbVie one better."[/i] http://www.chicagobusiness.com
AussieNeil
Administrator
in
CLL Support
8 years ago
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