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Abiraterone
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Prognostic role of pretreatment derived neutrophil to lymphocyte ratio in urological cancers.
I reviewed the PCa on ... 3 years ago: "
Inflammation. [1] Neutrophil-to-Lymphocyte Ratio [NLR]
" [2] with a follow-up a year later: "
Neutrophil-to-Lymphocyte ratio [NLR] &
." [3].
I reviewed the PCa on ... 3 years ago: "
Inflammation. [1] Neutrophil-to-Lymphocyte Ratio [NLR]
" [2] with a follow-up a year later: "
Neutrophil-to-Lymphocyte ratio [NLR] &
." [3].
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Zytiga resistance and Chemo
A genetic test showed he has a T878A alteration in his AR gene, which I believe means he is mcrpc and resistant to
abiraterone
. His doctor is starting him on taxotere on Sept 29th. I'm wondering if anyone is aware of any cross resistance that may impact the efficacy of chemo?
A genetic test showed he has a T878A alteration in his AR gene, which I believe means he is mcrpc and resistant to
abiraterone
. His doctor is starting him on taxotere on Sept 29th. I'm wondering if anyone is aware of any cross resistance that may impact the efficacy of chemo?
Dani2861
in
Advanced Prostate Cancer
5 years ago
My Bone Scans
The one on the right was taken after completing chemo, but before starting
Abiraterone
. There's still hot spots in there, but you can see the outline of my body, my kidneys are clearly visible in the back view, and my bladder is brightly shining from my crotch.
The one on the right was taken after completing chemo, but before starting
Abiraterone
. There's still hot spots in there, but you can see the outline of my body, my kidneys are clearly visible in the back view, and my bladder is brightly shining from my crotch.
tom67inMA
in
Advanced Prostate Cancer
5 years ago
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Veru-111 Advice
He has castration-resistant prostate cancer with progression despite
abiraterone
, enzalutamide, and docetaxel chemotherapy. About 4 months ago, he began treatment with radium-223, and has received 5 of 6 infusions thus far. His oncologist does not feel he needs to complete the 6th.
He has castration-resistant prostate cancer with progression despite
abiraterone
, enzalutamide, and docetaxel chemotherapy. About 4 months ago, he began treatment with radium-223, and has received 5 of 6 infusions thus far. His oncologist does not feel he needs to complete the 6th.
Amandaslp78
in
Advanced Prostate Cancer
5 years ago
Abiraterone in "High-" and "Low-risk" Metastatic Hormone-sensitive PCa.
[Epub ahead of print]
in "High-" and "Low-risk" Metastatic Hormone-sensitive Prostate Cancer.
[Epub ahead of print]
in "High-" and "Low-risk" Metastatic Hormone-sensitive Prostate Cancer.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Is BAT repeatable?
It should be born in mind that the BAT treatment has so far been shown to be helpful in cases of resistance to
abiraterone
and enzalutamide. Mine is the first “experiment” I know of to use it to manage resistance to bicalutamide. I have not been exposed to abi or enza (or chemo for that matter).
It should be born in mind that the BAT treatment has so far been shown to be helpful in cases of resistance to
abiraterone
and enzalutamide. Mine is the first “experiment” I know of to use it to manage resistance to bicalutamide. I have not been exposed to abi or enza (or chemo for that matter).
kaptank
in
Advanced Prostate Cancer
5 years ago
Enzalutamide + Abiraterone Acetate in Bone CRPC
INTERVENTION: Enzalutamide 160mg and
abiraterone
acetate 1000mg once daily; prednisone 5mg twice daily.
INTERVENTION: Enzalutamide 160mg and
abiraterone
acetate 1000mg once daily; prednisone 5mg twice daily.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Abiraterone self pay
Does anybody have a source to buy
Abiraterone
? We currently buy the Glenmark brand from India at a cost of $470 for two bottles (240 tablets) including shipping. If anybody has a cheaper and still reliable source please do share.
Does anybody have a source to buy
Abiraterone
? We currently buy the Glenmark brand from India at a cost of $470 for two bottles (240 tablets) including shipping. If anybody has a cheaper and still reliable source please do share.
taylor123
in
Advanced Prostate Cancer
5 years ago
Radium-223 in Clinical Practice. Video
"Surprisingly, the trial was unblinded prematurely after more fractures and deaths were observed in the
abiraterone
/radium-223 group than in the
abiraterone
/placebo group.
"Surprisingly, the trial was unblinded prematurely after more fractures and deaths were observed in the
abiraterone
/radium-223 group than in the
abiraterone
/placebo group.
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Olaparib Phase III trial
Lynparza Phase III PROfound trial in HRR vs. enzalutamide or
abiraterone
Maybe this positive result from a phase III trial could help some of you? https://otp.tools.investis.com/clients/uk/astrazeneca/rns/regulatory-story.aspx?
Lynparza Phase III PROfound trial in HRR vs. enzalutamide or
abiraterone
Maybe this positive result from a phase III trial could help some of you? https://otp.tools.investis.com/clients/uk/astrazeneca/rns/regulatory-story.aspx?
Claud68
in
Advanced Prostate Cancer
5 years ago
Zometa for bone strength to be given only with multiple bone Mets or to all stage 4 patients ? Even stage 4 with multiple lymph node Mets ?
His initial psa was 114 ng/ml, Gleason 4+4, he got orchiectomy and Casodex n within 3 weeks Psa was down to 4.66 ng/ml and is now on 1000 mg
Abiraterone
and 10 mg prednisone for 2 weeks. He got his dental cap refilling done as his MO said he may consider giving him zometa IV for bone strength.
His initial psa was 114 ng/ml, Gleason 4+4, he got orchiectomy and Casodex n within 3 weeks Psa was down to 4.66 ng/ml and is now on 1000 mg
Abiraterone
and 10 mg prednisone for 2 weeks. He got his dental cap refilling done as his MO said he may consider giving him zometa IV for bone strength.
Life5
in
Advanced Prostate Cancer
5 years ago
Yet another generic Zytiga question.
Any new general recommendations re generic
Abiraterone
vs. Zytiga?
Any new general recommendations re generic
Abiraterone
vs. Zytiga?
Gearhead
in
Advanced Prostate Cancer
5 years ago
Glucocorticoid Regimens in Combination With Abiraterone Acetate (Zytiga)
abiraterone
acetate 1000 mg daily: prednisone 5 mg daily; prednisone 5 mg twice daily; prednisone 2.5 mg twice daily; or dexamethasone 0.5 mg.
abiraterone
acetate 1000 mg daily: prednisone 5 mg daily; prednisone 5 mg twice daily; prednisone 2.5 mg twice daily; or dexamethasone 0.5 mg.
cbgjr
in
Advanced Prostate Cancer
5 years ago
Anti-Androgen Abiraterone Acetate Improves the Therapeutic Efficacy of Statins on Castration-Resistant Prostate Cancer Cells.
Importantly, in combination treatments, statins specifically enhanced growth suppression with added effects by anti-androgen
abiraterone
acetate on the CR PCa cells. Thus, statins can be used in conjunction with
abiraterone
acetate to enhance anti-androgen therapy for CR PCa."
Importantly, in combination treatments, statins specifically enhanced growth suppression with added effects by anti-androgen
abiraterone
acetate on the CR PCa cells. Thus, statins can be used in conjunction with
abiraterone
acetate to enhance anti-androgen therapy for CR PCa."
pjoshea13
in
Advanced Prostate Cancer
5 years ago
PSA and UTI
He has been on
Abiraterone
for almost a year and his PSA had slowly been falling from 42 down to 4, before this most recent jump to 19.5.
He has been on
Abiraterone
for almost a year and his PSA had slowly been falling from 42 down to 4, before this most recent jump to 19.5.
Dani2861
in
Advanced Prostate Cancer
5 years ago
To Provenge or not?
Consider a clinical trial involving
abiraterone
plus “X.” But this means waiting until PSA hits 2.0 for most clinical trials. Why should I wait until PSA is >2.0? We know I am now castrate resistant. And why not Provenge? It has been shown to prolong life >1 year for men with PSA<20.
Consider a clinical trial involving
abiraterone
plus “X.” But this means waiting until PSA hits 2.0 for most clinical trials. Why should I wait until PSA is >2.0? We know I am now castrate resistant. And why not Provenge? It has been shown to prolong life >1 year for men with PSA<20.
tallguy2
in
Advanced Prostate Cancer
5 years ago
Abiraterone added to Lupron
Is
Abiraterone
( Zytiga ) a pill? and did it that the place of docetaxel based on the stampede trial? Does medicare cover
Abiraterone
? Did the new research ( stampede) suggest that Abriraterone is better than docetaxel? Are the side effect less of an impact than the docetaxel? Thanks...
Is
Abiraterone
( Zytiga ) a pill? and did it that the place of docetaxel based on the stampede trial? Does medicare cover
Abiraterone
? Did the new research ( stampede) suggest that Abriraterone is better than docetaxel? Are the side effect less of an impact than the docetaxel? Thanks...
ken12491
in
Advanced Prostate Cancer
5 years ago
Merits of generic abiraterone acetate vs. Zytiga
I have been taking 1000 mg of Zytiga since early May this year. Now I see that several firms sell generics: Mylan, Apotex, Hikma, Teva, Patriot. I expect the efficacy and side effects would be the same, but the exorbitant cost would be considerably reduced. Am in the USA, and gross cost of Zytiga
I have been taking 1000 mg of Zytiga since early May this year. Now I see that several firms sell generics: Mylan, Apotex, Hikma, Teva, Patriot. I expect the efficacy and side effects would be the same, but the exorbitant cost would be considerably reduced. Am in the USA, and gross cost of Zytiga
bloodyveinpoke
in
Advanced Prostate Cancer
5 years ago
Add-on Onvansertib Overcomes Resistance to Zytiga in mCRPC, Early Data Show
2019/09/04/add-on-onvansertib-overcomes-resistance-to-zytiga-in-mcrpc-early-data-show/ Add-on Onvansertib Overcomes Resistance to Zytiga in mCRPC, Early Data Show Sep 04, 2019 01:03 pm | Jose Marques Lopes, PhD Onvansertib Adding the investigational oral therapy onvansertib to a regimen of Zytiga (
abiraterone
2019/09/04/add-on-onvansertib-overcomes-resistance-to-zytiga-in-mcrpc-early-data-show/ Add-on Onvansertib Overcomes Resistance to Zytiga in mCRPC, Early Data Show Sep 04, 2019 01:03 pm | Jose Marques Lopes, PhD Onvansertib Adding the investigational oral therapy onvansertib to a regimen of Zytiga (
abiraterone
JLS1
in
Advanced Prostate Cancer
5 years ago
Next Step
He has castration-resistant prostate cancer with progression despite
abiraterone
, enzalutamide, and docetaxel chemotherapy. About 4 months ago, he began treatment with radium-223, and has received 4 of 6 infusions thus far.
He has castration-resistant prostate cancer with progression despite
abiraterone
, enzalutamide, and docetaxel chemotherapy. About 4 months ago, he began treatment with radium-223, and has received 4 of 6 infusions thus far.
Amandaslp78
in
Advanced Prostate Cancer
5 years ago
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