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Abiraterone acetate [Zytiga] & food effect.
Abstract
Abiraterone
acetate, marketed as Zytiga®, is an antiandrogen medication used in the treatment of prostate cancer.
Abiraterone
acetate is a BCS Class IV compound associated with several oral delivery challenges.
Abstract
Abiraterone
acetate, marketed as Zytiga®, is an antiandrogen medication used in the treatment of prostate cancer.
Abiraterone
acetate is a BCS Class IV compound associated with several oral delivery challenges.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
#worldcancerday. Did Surf City marathon on 02/02
With T at 6 from
Abiraterone
(been on it 2 weeks), it was a bit of a struggle to finish under 7 hrs(6:59:0).
With T at 6 from
Abiraterone
(been on it 2 weeks), it was a bit of a struggle to finish under 7 hrs(6:59:0).
dockam
in
Advanced Prostate Cancer
4 years ago
Prognostic Nutritional Index (PNI)
There is also another earlier 2017 paper, for advance PCa titled: "Prognostic nutritional index predicts initial response to treatment and prognosis in metastatic castration‐resistant prostate cancer patients treated with
abiraterone
". https://onlinelibrary.wiley.com/doi/abs/10.1002/pros.23381
There is also another earlier 2017 paper, for advance PCa titled: "Prognostic nutritional index predicts initial response to treatment and prognosis in metastatic castration‐resistant prostate cancer patients treated with
abiraterone
". https://onlinelibrary.wiley.com/doi/abs/10.1002/pros.23381
Hidden
in
Advanced Prostate Cancer
4 years ago
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Veru Initiates Phase 2 Clinical Trial of VERU-111, First-in-Class, Oral, Advanced Prostate Cancer Drug
term=Veru-111&rank=1 Sounds safe, even for those with very low blood counts: "In preclinical effectiveness and toxicity studies, orally administered VERU-111 demonstrated significant antitumor activity against castration and novel androgen blocking agent (
abiraterone
or enzalutamide) resistant human
term=Veru-111&rank=1 Sounds safe, even for those with very low blood counts: "In preclinical effectiveness and toxicity studies, orally administered VERU-111 demonstrated significant antitumor activity against castration and novel androgen blocking agent (
abiraterone
or enzalutamide) resistant human
JLS1
in
Advanced Prostate Cancer
4 years ago
Statin use in advanced PCA with ADT or abiraterone/enzalutamide
KEYWORDS:
abiraterone
; androgen deprivation therapy; meta-analysis; prostate cancer; statin PMID: 31951037 DOI: 10.1111/jcpt.13092
KEYWORDS:
abiraterone
; androgen deprivation therapy; meta-analysis; prostate cancer; statin PMID: 31951037 DOI: 10.1111/jcpt.13092
pjoshea13
in
Advanced Prostate Cancer
4 years ago
End of Abiraterone - a question to the knowledgeable guys here
less than 0.03 Sep 2019:less than 0.03 Jan 2020:less than 0.03 During my last visit to MO, she told me that
Abiraterone
will be stopped (depending on imaging) at May 2020 which is two years since I started it.
less than 0.03 Sep 2019:less than 0.03 Jan 2020:less than 0.03 During my last visit to MO, she told me that
Abiraterone
will be stopped (depending on imaging) at May 2020 which is two years since I started it.
dorke
in
Advanced Prostate Cancer
4 years ago
Promising Clinical Activity of Cabozantinib + ADT in Hormone-Naïve Metastatic Prostate Cancer
These data imply that cabozantinib could have a role earlier in the disease course, particularly in combination with epithelial-targeting agents such as
abiraterone
and docetaxel. Follow-up studies will be necessary to define such a role and the potential use of CAFs to guide therapy.
These data imply that cabozantinib could have a role earlier in the disease course, particularly in combination with epithelial-targeting agents such as
abiraterone
and docetaxel. Follow-up studies will be necessary to define such a role and the potential use of CAFs to guide therapy.
Balsam01
in
Advanced Prostate Cancer
4 years ago
Prednisone induced facial swelling
Anyone on prednisone and
abiraterone
suffering from face swelling? How to reduce prednisone induced swollen cheeks?
Anyone on prednisone and
abiraterone
suffering from face swelling? How to reduce prednisone induced swollen cheeks?
Vsahay
in
Advanced Prostate Cancer
4 years ago
Abiraterone
Please do not respond to post, I'm sending to the 1st person who responded!
Please do not respond to post, I'm sending to the 1st person who responded!
Hidden
in
Advanced Prostate Cancer
4 years ago
Appointment with MO what to do after abiraterone ( other version of zytiga )
few months back after remaining steady over 2 years from therapy it's 0.150 right now so I am wondering is
abiraterone
stopped working now?
few months back after remaining steady over 2 years from therapy it's 0.150 right now so I am wondering is
abiraterone
stopped working now?
Nirman
in
Advanced Prostate Cancer
4 years ago
Start on Abiraterone two years after Docetaxel?
My question is, do we think it is a good idea for my Dad to start
Abiraterone
as soon as possible (if indeed it is made available to him) before he becomes castrate resistant? Or should we just wait?
My question is, do we think it is a good idea for my Dad to start
Abiraterone
as soon as possible (if indeed it is made available to him) before he becomes castrate resistant? Or should we just wait?
Jlcwonderboy
in
Advanced Prostate Cancer
4 years ago
FDA Grants Priority Review to Olaparib for HRR-Mutant mCRPC - Targeted Oncology - January 20, 2020
The PROfound study showed that olaparib reduced the risk of disease progression or death by 66% compared with pcNHA (HR, 0.34; P <.0001) versus
abiraterone
or enzalutamide.
The PROfound study showed that olaparib reduced the risk of disease progression or death by 66% compared with pcNHA (HR, 0.34; P <.0001) versus
abiraterone
or enzalutamide.
cujoe
in
Fight Prostate Cancer
4 years ago
Abiraterone Acetate 250mg Tablets
I have 107 unused tablets, I will send to USA address Expiration date Oct 2020
I have 107 unused tablets, I will send to USA address Expiration date Oct 2020
Hidden
in
Advanced Prostate Cancer
4 years ago
When should the next set of scans be?
Then started
Abiraterone
(zytiga) on 11/1/19. PSA is currently 11 as of 12/24/19 My question is: when should his next scans be and WHAT should they be? (Bone scan? Another PET?) Really appreciate any opinions. Thank you!
Then started
Abiraterone
(zytiga) on 11/1/19. PSA is currently 11 as of 12/24/19 My question is: when should his next scans be and WHAT should they be? (Bone scan? Another PET?) Really appreciate any opinions. Thank you!
j5000
in
Advanced Prostate Cancer
4 years ago
niclosamide - UC Davis Clinical Trial......in edit, what about artemisinin, which works for dogs with bone cancer?
Besides the anti cancer mechanisms you outlined, PDMX1001/niclosamide can resensitize the cancer to
abiraterone
and enzalutamide They have shown in vitro that niclosamide can revert mechanisms in the cancer cells which make the cancer resistant to abi or enza.
Besides the anti cancer mechanisms you outlined, PDMX1001/niclosamide can resensitize the cancer to
abiraterone
and enzalutamide They have shown in vitro that niclosamide can revert mechanisms in the cancer cells which make the cancer resistant to abi or enza.
JLS1
in
Advanced Prostate Cancer
4 years ago
Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer
agent (
abiraterone
or enzalutamide).
agent (
abiraterone
or enzalutamide).
MateoBeach
in
Advanced Prostate Cancer
4 years ago
Bio-Chemical Relapse that's me 3rd recurrence. But Clinical Relapse? Help me understand.
I could or should do some research myself but my mind is in on overload with
Abiraterone
and Prednisone 18 days in and still forcing me to exercise 2X daily. Any places I could look for mind overload EEC Doug?
I could or should do some research myself but my mind is in on overload with
Abiraterone
and Prednisone 18 days in and still forcing me to exercise 2X daily. Any places I could look for mind overload EEC Doug?
depotdoug
in
Advanced Prostate Cancer
4 years ago
Dr says Enzalutimide... what about Cabazitaxel?
prostate cancer who had been previously treated with docetaxel and the alternative androgen-signaling-targeted agent (
abiraterone
or enzalutamide)."
prostate cancer who had been previously treated with docetaxel and the alternative androgen-signaling-targeted agent (
abiraterone
or enzalutamide)."
Tak-Druk
in
Advanced Prostate Cancer
4 years ago
Rising creatinine with zoledronic acid infusions...
(on
abiraterone
for past 1 year and psa started rising this june.doc has advised to continue taking
abiraterone
and has prescribed zoledronic infusions).
(on
abiraterone
for past 1 year and psa started rising this june.doc has advised to continue taking
abiraterone
and has prescribed zoledronic infusions).
Vsahay
in
Advanced Prostate Cancer
4 years ago
PCa advice
I have heard other members start off with HT and
Abiraterone
or something similar and wondered why you would pick one over the other. 2) oligometatasis talks about 5 hot spots or less. Is there any clarification on the size of these spots?
I have heard other members start off with HT and
Abiraterone
or something similar and wondered why you would pick one over the other. 2) oligometatasis talks about 5 hot spots or less. Is there any clarification on the size of these spots?
SC19
in
Advanced Prostate Cancer
4 years ago
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