Associated Pyoderma Gangrenosum, Erythema Elevatum Diutinum, and Chronic Recurrent Annular Dermatosis: The Neutrophilic Disease Spectrum

[Shell567]

Very unusual!

Associated Pyoderma Gangrenosum, Erythema Elevatum Diutinum, and Chronic Recurrent Annular Dermatosis: The Neutrophilic Disease Spectrum, JAN 2022.

3 TYPES OF NEUTROPHILIC DERMATOSIS IN ONE PATIENT.

"Neutrophilic dermatoses (ND) are a set of clinically heterogeneous diseases characterized by the presence of a histologic neutrophilic infiltration with no identifiable cause. Previously described as independent entities, they are now considered a continuous spectrum of clinical entities. This concept is supported by the existence of different forms of overlap, as evidenced by the case we report. Our patient presented successively with three forms of ND."

"CRAND was first described in 1989 by Christensen et al. This entity is usually described as a subtype of SS (SWEET'S SYNDROME). To our knowledge, less than 10 cases have been reported." cureus.com/articles/81383-a...

[Luvmickeymouse]

I was diagnosed with Subcutaneous Sweets 8 years ago and recently diagnosed with Pyoderma Gangrenosum is this what your post is about or is it possible I had the wrong diagnosis?

[Shell567 Administrator Sweet's Syndrome UK in reply to Luvmickeymouse]

Hi Luvmickeymouse,

It's possible to have more than one form of neutrophilic dermatosis at the same time. The patient in the article has 3 (pyoderma gangrenosum, erythema elevatum diutinum, and chronic recurrent annular dermatosis. CRAND is a form of Sweet's syndrome that causes chronic, recurrent, ring-shaped skin lesions).

You have two different forms of neutrophilic dermatosis - pyoderma gangrenosum, and subcutaneous Sweet's syndrome (also known as Sweet's panniculitis). Subcutaneous Sweet's is a form of Sweet's syndrome that affects subcutaneous fat - fatty tissue under the 2 upper skin layers. dermnetnz.org/topics/neutro...