WHAT IS CREST?

[foxglove]

[Hidden]

From Wikipedia. A direct quote.

It is a form of systemic scleroderma associated with antibodies against centromeres and usually spares the kidneys. If the lungs are involved it is usually in the form of pulmonary arterial hypertension.

CREST is a systemic inflammatory rheumatic disease and usually results in more pathologies than the five symptoms above.

Patients with lcSSc commonly and slowly produce a pulmonary artery hypertension which can result in heart failure. Blood vessel thrombosis and arteriosclerosis has also led to the necessity of amputation of fingers. Open leg sores can result from burst blood vessels and thin skin, leading to chronic infections. Other symptoms of CREST patients can be exhaustion, weakness, difficulties with breathing, dizziness and badly healing wounds.

The origin of CREST lies in the immune system. There is production of anti-nuclear and anti-centromere antibodies, although it is not known if these antibodies are involved in the cause of the symptoms of the disease. There is no known infectious cause.

There is no cure for this disease as there is no cure for scleroderma in general. It slowly progresses and should be examined and treated as soon as it has been diagnosed with immunosuppressives and other medications. There are treatments that can ameliorate the symptoms of esophageal reflux, pulmonary hypertension and Raynaud phenomonon

[AliW]

raynauds.org.uk/scleroderma...

Hi there THis link should (I hope ) take you to the Raynuads page.

Take Care

AliW

P.s I have CREST if you'd like to chat let me know-

[Emma2]

I also have CREST too and am happy to offer any opinions, thoughts or advice which may help. It is such an odd condition that it useful to speak to other sufferers - you are definitely not alone.