curious question

[lorri214]

I was wondering. If mirapax is so bad for you, what happens to the parkinsons patients that must take it? Is that different?

[SueJohnson]

People who have both Parkinson's and RLS don't typically get augmentation.

[ChrisColumbus]

It has been widely shown that dopamine agonists - including pramipexole (Mirapex, Mirapexin, Sifrol etc), ropinirole (Requip, Repreve, Ronirol etc) and rotigotine (Neupro, Leganto etc) - ultimately make RLS worse, and also can cause Impulse Control Disorders (ICD).

They have also been linked to impulsive & compulsive behaviours in Parkinson's, but not to augmentation.

See also Dr Berkowski's paper last week, following SLEEP 2024, confirming that DA's are no longer recommended for RLS:

healthunlocked.com/rlsuk/po...