Targeted+systematic biopsy is the best

[witantric]

Interesting. Targeted+systematic biopsy seems to be the best.

directorsblog.nih.gov/tag/p...

Maybe this should be a requirement to go on AS.

[Tall_Allen]

More recent and MUCH larger trial (37,887 randomized men - entire male 50-60 yo population of Gothenburg, Sweden) proved that PSA> 3 + mpMRI-targeted only is better at finding significant PCa while ignoring insignificant PCa:

nejm.org/doi/full/10.1056/N...

I think it is still important to have a confirmatory mpMRI-targeted biopsy within a year.

[witantric in reply to Tall_Allen]

Thanks TA. As usual, you are a font of information.