PyL PSMA Pet/CT per UCF on YouTube

[jjpeabody]

I saw a video on YouTube today, "Grand Rounds in Urology" interviewing doctor from UCSF re PsL PSMA Pet/Ct, not approved yet. Basically longer half life and maybe better resolution than other PSMA but not necessarily more effective, too early to tell. Check out video for more info. A couple things I found interesting in general, Dr. Carroll from UCSF said lowest PSA valid for PSMA scans would start around .15-.2 and would expect 40-50% effective. Also stated that for recurrence after RP, not sure about specifics of cancer, he said that recurrence in the prostate bed is more uncommon than might be expected and that cancer in the pelvic lymph nodes would be higher. Check out video if any questions, it was 13 minutes and interesting but not sure my comments does it justice, mainly FYI. Personally I called UCLA to check on status of my referral from late last week and they said no record of anything. Had doctor re-fax referral to scheduling this morning and they called me back this afternoon with an appointment for March 15. While they do have you pay when you arrive and sign a waiver, the scheduler told me they would forward info to Medicare and ball would be in their court, however no knowledge or expectation to be reimbursed. Good luck, Jim

[Tall_Allen]

There was a head-to-head trial in which PyL detected more lesions:

prostatecancer.news/2016/12...

[jjpeabody in reply to Tall_Allen]

Thanks for the reply and info, I had no idea. Video seemed recent but after this link to 2016, I don't know what to think. Radiation oncologists seem over confident my recurrence is in prostate bed. Due to Gleason 4+3=7, PSDAT, recurrence in 21 months, extra-capsular extension with negative margins, and perineural invasion I am giving PSMA Pet at UCLA a try. By March I expect PSA to be above. 2 but will have checked a week or so before. Per your suggestion I did namogram on longevity and by doing nothing I had 46% chance to survive 10 years and I think dying of PCa was only 17%. I plan on 10 good years conservatively and feel reluctant to try SRT to prostate bed only at this time. Spread to lymph nodes may be a self-fulfilling prophecy by postponing. It feels kind of like rocket science.

[Justfor_ in reply to jjpeabody]

I am just right behind you, although higher risk (GS 4+5, pT3b, RP May 2019, latest PSA 0.11). My plan includes one month of Casodex prior to PSMA PET/CT in hope of stimulating a bit PSMA avidity. Saving your post so as to ask for your results in March. Wishing a conclusive detection!

[jjpeabody in reply to Justfor_]

Thanks for your reply Justfor, I am not-so-patiently waiting for my scan. I will definitely post results within a day or so after receiving. I will then post my proposed treatment plan for comment hopefully. Good luck.