"October 13, 2020 -- A PET-based optical imaging technique called Cerenkov luminescence imaging (CLI) was successfully used by German researchers to confirm the presence of cancer cells after prostate cancer surgery, according to a study published in the October edition of the Journal of Nuclear Medicine.
Researchers from the University Medical Center Essen tested the use of Cerenkov luminescence imaging in a small group of 10 patients with high-risk primary prostate cancer (Journal of Nuclear Medicine, October 2020, Vol. 61:10, pp. 1500-1506). The goal of the study authors was to see if CLI could accurately detect surgical margins during radical prostatectomy and to indicate whether residual cancer remained after the surgery."
"The researchers concluded that intraoperative Cerenkov luminescence imaging could improve the accuracy and safety of radical prostatectomy, especially in high-risk prostate cancer patients. They also suggested that targeted surgical removal of lymph node metastases could be performed with CLI."