Is it hereditary?: Both sets of my Grandparents and... - PMRGCAuk

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Is it hereditary?

TiaPasha profile image
11 Replies

Both sets of my Grandparents and my father came from Scandinavia, my Gran was Swedish so when I read I ticked a few boxes I of course thought why? Would be interested to hear any thoughts on this and possible answers.

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TiaPasha profile image
TiaPasha
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11 Replies
DorsetLady profile image
DorsetLadyPMRGCAuk volunteer

See this lighthearted look at subject penned many moons ago -but yes more prevalent in those with Northern European heritage -

healthunlocked.com/pmrgcauk...

TiaPasha profile image
TiaPasha in reply to DorsetLady

Wide awake at midnight of course and just read it, love it. I was given one of those ancestry kit things last year so did the test. I sent the pic of the map to my daughters saying, “that is why we are so bossy”. Or is it that we are always right?

DorsetLady profile image
DorsetLadyPMRGCAuk volunteer in reply to TiaPasha

Always right of course…😊

Suet3942 profile image
Suet3942 in reply to TiaPasha

Yeah I had my DNA checked and found I am 38% Scandinavian. As my maternal grandfather was born in the wrong side of the blanket I can’t trace back any further than his birth.

AtopicGuy profile image
AtopicGuy in reply to Suet3942

Don't despair! One of my ancestors was born illegitimate, and was then abandoned as a baby. They were raised in an orphanage and died never knowing either of their parents. I sent my DNA to both 23&Me and Ancestry.com, revealing living relatives across the world. After a lot of detective work, I identified both the mother (whose name was on the birth certificate) and, to my amazement, the father (whose name wasn't).

PMRpro profile image
PMRproAmbassador

It isn't hereditary in the true sense of the word - a disorder where a specific gene causes the illness as you see in cystic fibrosis or muscular dystrophy.

It has a genetic component where there is a constellation of genes that creates an environment where it is more likely that if a range of conditions are fulfilled - environmental, chemical, infection, all sorts of things that can stress the immune system, that it will tip over the edge and go haywire. But the set of genes and the set of triggers must coincide at some point and even then, two people with the same prerequisites won't necessarily both develop PMR.

Markandevie profile image
Markandevie

I did a DNA test and I resulted in 24% Scandinavian and maybe this is why I too were diagnosed with PMR .

pats000paints profile image
pats000paints

I had a Swedish grandfather on my dad's side. My father developed PMR at 65 and I did the same.

My mother also had Scandi ancestry. According to my DNA, I'm 52% Scandanavian.

As far as I know, its a disease of the white race. Black folks don't generally get it.

Tiredcat profile image
Tiredcat

My mother, brother and I have all had PMR. Any further back didnt live long enough to develop it.

My grandmother came from Waterford in Ireland, which became a Viking stronghold, as I understand it. The northeast of England was too, and I understand PMR is more prevalent there too.

PMRpro profile image
PMRproAmbassador in reply to Tiredcat

Except the figures suggest there are far more diagnoses of PMR in the SE and south of England than in the north. I think it is because northerners don't go to the doctor but put it down to aging - and my GP certainly tried to! There is actually a study being done at present - though I am far from sure they are asking the right question ...

DorsetLady profile image
DorsetLadyPMRGCAuk volunteer in reply to Tiredcat

Actually we have evidence of Vikings in Dorset- and not just the modern ones!

Burial site found in 2009 of 54 skeletons(thought to have been massacred by local Anglo Saxons) between Weymouth and Dorchester.

Fortunately the locals are more friendly nowadays…😊

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