How do people tapering from PMA stand with regard to Covid vaccines? Are there differences between vaccines in respect of their suitability for pred users?
PMA and Vaccines: How do people tapering from PMA... - PMRGCAuk
PMA and Vaccines
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Montplo
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I don’t think there will be a choice! It’s quite a feat just to get the one out for mass vaccination. It isn’t a live vaccine so doesn’t have the usual problem associated with immunocompromised people. Any vaccine stimulates the immune system otherwise they won’t work, so that aspect may or may not trigger yours unfavourably. Many forum users happily have the flu jab and pneumococcal jabs every year. As for technical differences between the different companies’ offerings, I don’t think the public are party to that info yet. There are lots of discussions on this topic which you can find by searching this site with words like “Covid vaccine” or “vaccination”.
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No-one knows those sort of details yet, But if you have the flu vaccine - there is likely to be no reason why you shouldn't have the Covid vaccine.
When they say that these vaccines will not be given to immunocompromised patients they don't mean us, they mean patients with HIV/AIDS, after solid organ transplants, cancer and renal patients and with congenital immunoglobulin deficiences. Those are all a very different level of immunosuppression.
True - but I would like to know if the coronavirus uses reverse transcriptase as does HIV. I have searched the literature to no avail.
dw.com/en/whats-the-science...
"HIV, for instance, has a "reverse transcriptase," which copies the viral genetic material back into the genome. But viruses like the coronavirus or influenza don't have that, says Doherty.
"So, we're not going to copy the genetic material back into the human genome. But quite frankly, if you made a RNA vaccine and you gave it to people and it transmitted to other people, that would be a good thing," he says. "But I don't see why it should happen anyway." "
Is that what you mean?
There are several different types of vaccines in the pipeline. I think we are sensible to be wary of the RNA oone as it's new and never been used in humans before. On the other hand we have to trust that no health authority is going to unleash any vaccine on the public without thoroughy studying the data and determining it is safe. No company will want to be responsible for any kind of vaccine-related disaster. I personally will be watching from afar the results of vaccines given to vulnerable populations in other countries while I await my turn in Canada. No haste!
It has - mRNA vaccines are at advanced stages of clinical trials for HIV.
Same thing then, "advanced clinical trials". Considering the UK only just approved the new vaccine, and other countries haven't yet although working on it, it seems pretty much the same to me.
Don't seem to be able to "edit" today. I guess in many ways the first wave ot vaccination is part of the testing although no one really wants to admit it. I am rather glad I am not over 80 and living in a nursing home just waiting to be a guinea pig. But give me a few months of observation and nothing untoward emerging, I'll be first in line for vaccination. Kind of hope the Canadian one in stage three trials makes it and gets the green light. "Virus-like particles" another experimental type I think?
It is to be hoped everyone else doesn't do the same ...
i don't think there will be many people in old folks homes passing up the chance to be able to have visitors again, and if said visitors also have to be vaccinated, most of them will be. Thankfully no one in our family is in such a situation. Sorry if that sounds callous. On the other hand I'm not sure I understand why governments are falling over themselves trying to get the least convenient, possibly most expensive version of vaccine rolled out.
Because it is the first to complete approval, it is in Europe and the Moderna one is already under contract to the USA in vast amounts.
They won the race. It will also be a boon to manufacturers of the special refrigerators, and pretty much useless in huge swathes of the world. Do we know if it's going to turn out to be the best one? I know everyone wants a vaccine yesterday but this scramble is actually making me a bit nervous. I'd rather wait and see how the other types measure up. The mess with the Oxford one where (serendipitously it turns out) the wrong dose was given to some of the trial subjects is concerning. At that level there should have been no mistakes. But perhaps the hand of fate dealt a good hand there?
Hi all, I have read some and am by no means an expert. My understanding is the first vaccines out are mRNA and will work by entering your cell and using your genetic material to make a covid protein. After that it is released then an antibody is created using the hosts immune system. I believe this science is relatively new. I would appreciate any input as this is advanced and different then I expected from a vaccine.
That is sure what it sounds like. modernatx.com/mrna-technolo...
Hi Heron, I just read a NYT article and that is how they described the Pfizer vaccine. RNA is introduced and our cells produce the covid protein and then the antibody against it. Sounds a lot like an autoimmune disease to me.
That's what long Covid probably is. There must be a possibility that this could be the basis for a way of treating a/i disease. It is in use for cancer therapies.
Is long Covid when people don’t recover? Is this an autoimmune condition? Interesting!
Saw this and thought it interesting. cbc.ca/news/canada/sudbury/...
Sounds like PMR!!
I don't know. That brain issue where the patient for months felt disconnected from her body. That sounds more like the short-lived sensation I'd get when I bumped my head as a child, not the sort of "what word am I looking for" sensation of addled PMR sufferer.
Is that why I can't find words? I thought it was my ahe
Is this a side effect of prendisolone or PMR?
Great question and something to think about. Im sure they havent thought it all through to that Point yet.
Spoke to my rheumatologist on Saturday and asked about vaccine, she said they will to decide which is suitable for those on steroids and so will not be in the first waves, they have been tested on elderly people and so can start vaccinating now
Here is the link to an article that describes what to look for in Covid-19 vaccine first trails written in plain language by Alan McGreevy, Instructor in Biology, University of Winnipeg. It may answer some of the questions posted here
I read a while back on the BBC news website that there was a trial going on for people who couldn't have the vaccine which was injecting people with anti bodies directly into the muscle. They are hoping it will give instant protection but may only last a year, it would only be available to people with conditions that cannot have the vaccine because it would cost more.
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