Can you test for anti-intrinsic factor antibodies while injecting?

[fx9898]

Can you test for anti-intrinsic factor antibodies while injecting?

[Nackapan]

I assume so.

High levels s of B12 can possibly give a false positive I've read on here

Mostly done before loading Doses start.

However many surgeries are wanting B12 levels done and IFAB as a way wrongly to stop b12 injections if b12 in range 🤔 and IFAB negative.

Ignorance at its worst 🙃

[helvella]

Someone asked this the other day. My reply was pretty much that if they need to know with any certainty, contact the lab.

They were tenacious and did get through. That lab said it was not an issue.

Memory is that it has been an issue but that is all too fallible! Maybe it used to be? Maybe it depends on actual test kit? Maybe it is never a problem?

[Technoid in reply to helvella]

^ Agreed - check with the lab - It depends on the test they use as far as I know.

[tattybogle in reply to Technoid]

yes , i eventually got through to the lab that does this test in my area (not the same lab that does my thyroid bloods, i had to go via 'immunology' depti think ,but i've forgotten now cos it took multiple calls to find the lab) ... clinical scientist told me that the test their lab uses now is not affected by loading dose injections , but the one they used previously was. So it depends which test the lab is using.

[Gambit62 Administrator]

As above you need to check with lab. IFAB can give false positives if done too close to an injection but exactly what constitutes too close depends on the exact test methodology and that depends on the exact equipment that is being used in the lab. For old equipment it was a couple of weeks - for new equipment it is a lot less.

[Orchard33]

The protocol my GP practice followed was to test three months after injections began. No idea why. In the NHS it seems that protocols are not questioned. My test was negative but my GP treated me as if I have PA with loaders and then 3 monthly, later negotiated to 2 monthly. Lamentably insufficient as I discovered. I self-inject every 2 to 3 days.

[fx9898 in reply to Orchard33]

How long have you been injecting? Are you really needing to do 2-3 days for the rest of your life?

[Orchard33 in reply to fx9898]

I don't know. I hope not but that is often how it is for people of this site.

[topazrat]

My surgery tested once before I started jabs and, for some reason, another within a few weeks of a jab. Both were positive. My cynical head thought that they were sort of hoping for a negative one second time around so that they had an excuse to stop my jabs. But of course, having had one positive test, that wouldn't have happened, would it? 😏

As it is, I keep having to remind them that I've had two positive tests and that they can't stop my jabs. They deny the results, and I have to tell them to search my notes, as they have conveniently dropped of the main page. I have printouts of them in case they ever get 'lost'.