Can B-12 Cyanocobalamin shots increase your Serum Cobalt levels?

[robinsnestwalke]

can anybody with pernicious anemia that gets b-12 monthly injections let me know if it could or would raise your cobalt serum levels? I had a DR run mine out of concern of a leaking hip that was done over 10 years ago.

Cobalt, Serum my value 3.0 UG/L standard <=1.0 UG/L

so it came back as flagged and he got me all concerned and did a 2nd replacement, but I was wondering if it was raised because of injection's. This after he already knew I got Cyanocobalamin shots for my disease.

[Gambit62 Administrator]

the amount of cobalt in cobalamin is very small and it is also very tightly bound in the molecule so it really shouldn't have affected the serum cobalt but I am not a medical expert. If you are concerned then best to speak to your doctor.

[robinsnestwalke in reply to Gambit62]

thank you for the response.

[fbirder]

Let's suppose your B12 injections boosted your levels to 6000 ng/L (way above the top of the range). Cobalt (atomic mass 59) represents 59/1355 = 0.04 or 4% of cyanocobalamin, by mass.

So 6000 ng/L of cyanocobalamin would be the same as 240 ng of cobalt per L. That is less than 10% of your value of 3,000 ng/L.

[robinsnestwalke in reply to fbirder]

I figured I'd get a response from you fbirder, as my memory serves me I think you are a chemist or something along those lines. Sounds like it did come from the hip. thank you.