The Many Faces of B12 Deficiency (paper from the Mayo clinic)

[MoKayD]

Has anyone seen this paper from the Mayo Clinic? ncbi.nlm.nih.gov/pmc/articl...

I liked the conclusions the authors are drawing from the latest B12 deficiency research.

[pvanderaa]

Good article that has examples where B12 was withdrawn after subsequent tests showed high B12. This withdrawal of B12 therapy resulted in worse neurological damage for the patient.

[Justiina]

Great article. Tomorrow I will check all mentioned genes from my raw data. I don't know why I keep looking for reason why I need B12. I just need it.

Btw I am on similar injection mentioned on the article B12+B1+B6.

[pitney]

Thank you

[helvella]

A quote from that paper (as a quote of a misunderstanding):

Oral therapy is as good as or even better than painful injections to alleviate neurologic symptoms

I hate it when the medical establishment twist things like this. Just take out one word:

Oral therapy is as good as or even better than injections to alleviate neurologic symptoms

The subjective painfulness of the injections, and we see here a huge range from hardly noticing to very painful, is utterly unreleated to the therapy being as good, or not. The "painful" word is included to push their narrative.

And if it is painful for your patients, review your injecting procedures!

(Yes, of course, everyone here agrees that oral therapy is not as good as injections.)

[Cherylclaire Forum Support in reply to helvella]

…...So how about when you need 3 months' worth of reloading injections at 2 per week before you are even able to tell that you're really being injected at all ?

Yes, finally I didn't have to ask "Have you done it yet ?" any more .

Good that it acknowledges that the only adverse effects ever reported, even at high doses of hydroxocobalamin, were spots.

Now can GPs all stop panicking please, so we can continue to save our own lives in peace ?

[ABluemoon]

Thank you so much for posting this info. It helps to explain a lot.

[kittyflowers]

A really educative and comprehensive article that should be useful to help us educate GPs too. Thank you for posting.

[Hidden]

Thank you for posting the link to this very enlightening paper from the Mayo Clinic. I enjoyed reading the myths table, and I find it refreshing that they use treatment of injections, two a week, till symptoms are gone, and seriously disagree with stopping injections or checking B12 levels once treatment has started. It would seem that a lot of our members are in tune with the Mayo Clinic's findings, and using this link should help with getting more frequent injections from stingy, uninformed doctors.

[Retteacher]

This is indeed a very useful article. However, it is important to be precise when quoting this to doctors or they will use errors to ignore the info. This article is not written by doctors from the Mayo Clinic. It is written by doctors from the Groningen Medical School in Amsterdam. The journal is published by the Mayo Clinic.

Also be careful to say that the article is based on extensive clinical experience and practice. Some GPs may say that the conclusions are not evidence based I.e. the result of double blind trials. Perhaps the riposte should be that' so UK patients have to have inferior care to Dutch patients?'

[Bluedragon]

Great article! Thanks for sharing.