hello i wondered if anyone new anything about diesel depleting b12 ?
diesel: hello i wondered if anyone new... - Pernicious Anaemi...
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lorna59
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Er, nope.
Sounds highly implausible. I guess the exhaust would contain small amounts of nitrous oxide, but modern engines use a catalytic converter to degrade that to N2 and O2. But even without a cat, the CO would be a lot more nasty than the N2O.
Gambit62Administrator
There have been concerns about the levels of emissions from cars - including nitrous oxide which doesn't deplete B12 but does render the B12 in your blood inactive.
These concerns have been increased following the recent scandals over rigging of emission tests in certain makes of cars.
However, I'd also be of the opinion that that carbon monoxide emissions are likely to affect you before nitrous oxide becomes a factor.
uk-air.defra.gov.uk/assets/...
p8 talks a bit about nitrous oxide - though most of the report is about nitrogen dioxide which doesn't have the same effect as nitrous oxide.
I would err on the side of caution and say we don’t know. B12 is known to bind to toxins which are then eliminated from our bodies via urination. Then there is the individual response.
I would think it not too farfetched to hypothesise that people with predisposed b12 d traits could become deficient with toxic overload from exposure to environmental toxins
One little known toxic mechanism of b12 d is from mould and its metabolites.
One little known toxic mechanism of b12 d is from mould and its metabolites.
I've not been able to find anything that definitively says that mycotoxins can cause B12 deficiency. I've found speculation and hand-waving.
Some have reported a correlation with B12 deficiency and patients complaining of chronic mycotoxin exposure. However, they haven't been able to demonstrate that the mycotoxins cause the B12 deficiency. It could be that people with an undiagnosed B12 deficiency (and we know there's a lot of those) are more susceptible to chronic toxigenic mold exposure.
I believe mould illness and b12 d are interconnected in many ways. One parallel is that both are poorly understood by clinicians and another is, both are commonly misdiagnosed. Together they probably account for over half the world’s chronic health problems. Both are multi system illnesses and there’s nothing quite like presenting symptoms from multiple systems to get your Doctor reaching under his desk for the psychosomatic button!
Mycotoxins in sufficient quantities will make anyone ill. However, it is now emerging that 24% of the population are genetically predisposed to bio-toxin illness. These people can’t clear the toxins and allergens from their systems, their body doesn’t recognise them and they build up to levels which cause ill-health.
There is a huge crossover over of symptoms and if mycotoxins affect b12 through one carbon metabolism, it could be opening the doors to functional deficiency. The Neurological deficits caused by mould are well documented but few papers explore the mechanisms. It is also documented that mould can trigger autoimmune diseases, although Doctors at the forefront of bio-toxin illness, CIRS are saying it is mimicking diseases like MS and RA.
Here are some links to papers, without re-reading them I’m sure it is Anyanwu who suggests mycotoxin testing for all b12 d diagnoses.
ncbi.nlm.nih.gov/pubmed/153...
ncbi.nlm.nih.gov/pubmed/179...
Dr Hope’s paper touches on multi-vitamin and antioxidant deficiency in WDB.
ncbi.nlm.nih.gov/pmc/articl...
Taking them in order -
Although, these roles (of B12) are evidently documented, the effects of
mycotoxins on them are yet to be fully realized in the light of ongoing research. However, the possible adverse interruption of these metabolic roles by mycotoxins have been assessed and evaluated.
Speculation with zero evidence.
A majority of patients with neurological disorders with chronic exposures to toxigenic molds and mycotoxins has vitamin B12 deficiency
Correlation does not mean cause. They need to show that people with B12 deficiency are not more likely to present with medical complaints of mycotoxin exposure. Being as undiagnosed B12 deficiency makes one feel crap it would not be surprising if it made one feel more crappy than a normal person when exposed to toxins of whatever type.
Paper 3 is a total re-hash of paper 2.
The final paper doesn't even mention B12.
An interesting question as my low B12 has occurred after buses began to run through our estate. These buses were increased in frequency (every 10mins) just over two years ago, coinciding with my low B12 diagnosis. They sit with engines running outside my house, and run at regular intervals from 5.30am until 11.30pm. I know from the amount of dirt collecting on my net curtains that there must be pollution. Incidentally I also developed asthma in this period.
