Do we all have to take sinemet? Is Rytary an alternative? Has anyone moved off sinemet and onto Rytary? In my last appointment, my neuro prescribed amantidine along with sinemet. As my sinemet wears off, I'd been getting a painful dystonia in my right foot. It is so bad I can't drive or walk. So far I see no effects, good or bad, from the amantidine. But sinemet -- ugh!