Rytary vs Sinemet : Has anyone compared... - Cure Parkinson's

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Rytary vs Sinemet

Mogul1 profile image
16 Replies

Has anyone compared these name brands as opposed to comparing generics? I’m going to switch from Rytary to Sinemet. For me , Rytary is bad news. Afraid it would cost me my marriage. Good C/L 50/200 is N/A in the PNW. Gotta go name brand in my opinion.

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Mogul1 profile image
Mogul1
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16 Replies
texasL profile image
texasL

My dad couldn't tolerate Sinemet. Now on Rytary. No side effects so far, but does nothing for his tremor.

Mogul1 profile image
Mogul1 in reply totexasL

Why couldn’t he tolerate Sinemet?

texasL profile image
texasL in reply toMogul1

Chest pain

Mogul1 profile image
Mogul1 in reply totexasL

I had not heard about chest pain.

Was his Dr. aware? Surprised?

texasL profile image
texasL in reply toMogul1

His doctor said that this is unusual side effect

Adnelg54 profile image
Adnelg54

There is no generic for rytary.... it’s only be out about 3 years

Mogul1 profile image
Mogul1

Thanks, I understand. That was aimed at Sinemet.

TexasTremor profile image
TexasTremor

I’ve been on both. Rytary is control release, I’m assuming you’re considering Sinemet C/R? Both worked well for me, as did Sinemet immediate release. I was on Sinemet IR for about 3 years, then my MDS switched me to CR for about 2 years. My dosages were high (between 2 and 3 grams a day - as needed) and still weren’t working 100%. No side effects for me. I’ve been on Rytary for the past year and am once again over 2 grams. Only side effect is minor reflux at times. Only drug that kicked my butt was Nupro (patch). It worked AMAZING but I literally spent about $300k in 8 months. That one was prescribed between Sinemet IR and CR timeframe. Rytary is a higher copay for me vs Sinemet.

What side effects did you get from Rytary that you’re hoping to avoid with Sinemet?

PDGal4 profile image
PDGal4 in reply toTexasTremor

Neupro manufacturer supplements cost for me, as does Rytary. Have you looked into? I am in the US, not on medicare.

Mogul1 profile image
Mogul1 in reply toTexasTremor

Thank you for the reply. When I began recognizing a pattern in the evening of feeling over-medicated, over-amped, edgy, easily agitated. My wife was seeing my personality change but the next morning I would be my old self but keenly aware that the previous night my conduct was unbecoming. It felt like the Rytary was stock-piling and all was releasing at days end. That was verified by my neurologist. He called it “Stacking”. Beware.

TexasTremor profile image
TexasTremor in reply toMogul1

Wow, definitely not good. I do notice Rytary doesn’t always release when I expected or needed it to or it feels like it never got me fully “on.” Brand name Sinemet released very consistently and fully for me but wore off rather quickly (the CR).

in reply toTexasTremor

To clarify, I think you meant that you spent all that money gambling or something else. Not on the medication, correct?

TexasTremor profile image
TexasTremor in reply to

Haha, yes. Amazon can use my workshop as a secondary warehouse!

Brills3 profile image
Brills3

What strength of the new Pro are you on? We have been on all dosages, and have some extras. They are expensive! Our current neurologist believes that they can be contributing to aspects of dementia, hallucinations which we are experiencing. We went from 6 mg to

Brills3 profile image
Brills3 in reply toBrills3

To a 4 mg. We are in austin.

horsplay profile image
horsplay

if you are in the us, check out myrytary.com. they can help you with the cost.

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