I just got out my journal from 2013, the year I was diagnosed. I was curious how long it had taken for the Sinemet to really make a difference in my symptoms. At our local support group we had a neurologist speak this week and he said it was a matter of hours in which people could see a difference. My neurologist at the time said it could take weeks. But reading my journal it took a long time for the Sinemet to really make a big difference. And it continued to get better until I was hiking again and biking 10 miles at a go, Etc. I'm glad I have this journal. It's fascinating to read. Every day in the beginning I talked about how I needed to push myself and get out more. I also talked about how exhausted I was. Parkinson's is one of the few things in life where if you're tired you get less tired by doing more... Up to a point, of course.
I would love to hear other people's experience with this.