Treating the root cause of reflux

[Mauser1905]

BMJ has below research posted which claims long term use of acid inhibitors/blockers doubling stomach cancer risk.

bmj.com/company/newsroom/lo...

Its heart wrenching to see majority patients suffering GERD, HH hanging onto use of PPIs and H2Ra's as some kind of magic solution. Fighting battles with different dosages and brands but losing out on war to oesophageal cancer.

This anatomical problem cant be fixed with manipulating acid production. Ling term manipulation has it's own side effects and perhaps onset to OC. Which happened to me.

Every time I see a new person having exact same symptoms going about the same route of experimentation of symptom management rather root cause fixing, frustrates me.

Anyways rant over for the day.

[jeffw663]

Hi, I do not understand your post, sorry, what are GERD, HH, PPIs, OC and H2Ra's ? had an Ivor Lewis last year and I am doing well, am taking a 40 mg Omeprazole each morning which is working well, no real problems with reflux, is this, in your opinion OK ??

[Mauser1905 in reply to jeffw663]

Jeff,

GERD gastro esophageal reflux disease

HH hiatus hernia

OC oesophageal cancer

PPI proton pump inhibitor ( prazole family drugs)

H2Ra histamine 2 receptor antagonists( commonly called as H2 blockers, from tidine family of drugs)

I am not an medical expert.

It is understood that after Ivor Lewis (IL) surgery the capability of the stomach to produce acid reduces significantly when compared to pre-surgery anatomy, there may be exceptions to this.

For daily use of 40mg prazole after one year post IL surgery seems exception in my opinion, but there may be reason.

The post reflect my personal agony after seeing many GERD, HH sufferers going similar pathway of mine while experimenting on variety of acid reflux (symptoms') treatments rather than getting an anatomical fix such as Nissen fundonplication or Linx band etc.

[jeffw663 in reply to Mauser1905]

Thanks Mauser, I now understand, I will ask about the prazole on my next check up.

Thank you Jeff

[Heathwaite in reply to jeffw663]

The majority of us have to take PPI s for life to give us a better quality of life and protect what is left of our Oesophagus so the benefits outweigh the risks.

This research was discussed in great detail when it was first published and many experts were convinced the searched was flawed including many consultants.so I would not worry about taking PPI s

Phil

[jeffw663 in reply to Heathwaite]

Thanks for your advice Phil, I get on very well with them and apart from 'dumping' lead quite a normal life and eat a wide range of foods from steaks to salads.

My thanks again

Jeff

[Janashlin in reply to jeffw663]

Jeff have you been able to figure out what causes the dumping and how to control? I am struggling with it at the moment. 4 months post IL

[jeffw663 in reply to Janashlin]

I am not aware of anyone who has had the I.L. op being 100% free of dumping, at our OPA meeting I met an old work mate who had the op 8 years ago and still has problems every morning. For me over eating can cause it but it can happen out of the blue and for no obvious reason, we just have to live with it, I have gone over 1 week no problem, then have it 2 days running (no pun intended !).

Jeff

[DavidP]

Turning the research on its head, it could be that patients receiving higher doses of more potent agents for longer reflect more severe underlying disease with consequent outcomes. A parallel would be a hospital that treats more severely ill patients and therefore ends up with a higher than average mortality rate - that doesn't mean it's a bad hospital. The research was not a prospective clinical trial so causality is not proven. I take your point about surgical manipulation but that isn't an option in most cases (like me) who discover they have OC without taking long-term acid suppressing agents.

David

[Mauser1905]

I am living example of developing adenocarcinoma of lower GR junction due to long term HH and GERD. Yes I was fortunate to get this discovered in time to get surgery. Neither GP/GI consultants nor surgeons have proven me wrong on my standing as above.

Long term PPI such as omeprazole can cause pneumonia and also erectile dysfunction as side effects.

I had adenocarcinoma of lower GE junction and not squamous cell carcinoma.