Leflunomide

[LucyZuma]

hello my RA doc prescribed me LEFLUNOMIDE to be take with hydroxychloroquine. Anyone else take this combination? I have been on hydroxychloroquine off and on for a couple of years. My hands and feet are getting stiff and sore again

[Kati66]

Hi Lucy

Yes I’m on both of those. I was on methotrexate initially then with hydroxychloroquine but came off metho due to side effects. I then went on Leflunomide instead and got on much better with it. However after a year, my bloods were not good so I’m waiting to go on a biological now. I haven’t had any side effects from the Leflunomide at all though.

[LucyZuma in reply to Kati66]

Hey thanks. I was on humira but had developed rashes had some bloody phlegm headaches and fatigue so go switched to enbrel and after a few months had a flare. Metho worked for a while but started affecting my liver. I’ve been at RA doc at least 3-4 times a year for the last 5 years. I hope this works out. I’m hoping to get to the point I only see RA doc once a year. I don’t want to take anymore injections. Basically I’m doing good. I walk at least 2 miles a day and have a healthy diet. Unfortunately I smoked for 30 years. It’s been 20 years since I quit. I’m getting stiff again. Maybe I shouldn’t have said that to doc. I’m afraid of another flare

[Hopeful1]

Me too. Triple therapy with sulphasalazine. Worked for several years. No side effects.

[LucyZuma]

thanks that’s good news. I have issues with sides effects on metho and humira and enbrel doesn’t work. Hydroxychloroquine is great but now I’m getting stiff again and afraid of another flare

[GenesisRevelation]

Leflunomide made my liver tests go way up! I got off it after 4 months. Be careful

[LucyZuma in reply to GenesisRevelation]

Thanks. This is good to know

[skinnycappuccino]

Hi LucyZuma

Yes, I'm on both Leflunomide and Hydroxy (and also Rinvoq). I have been taking this combination for years and it works really well for me with no side effects (except for a bit of nausea). Good luck with Leflunomide, I started taking it after I couldn't tolerate MTX and it's so much better (for me anyway)!! All the best, Christine xx