NRAS
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Humira stopped working, what’s next?

Hi everyone, I’m 44 years old living in Scotland. Been on Humira five years and it was life changing for me, worked so effectively and immediately.

However, around five weeks ago I suspected it was losing effectiveness as fatigue and painful fingers returned. Now, pain and swelling has spread to other joints. Called rheumatology nurse who said she’d try fit me in in couple weeks.

Has anyone been in this situation and successfully changed to another biologic? The thought of regressing to how I was before Humira terrifies me.

All advice welcome x

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Hi Wendy I'm on Benepali and Methetrexate, 7 months and 3years but I'm having the same problem as my fingers and hands are swollen and my joints are killing me, they gave me a steroid jag in January to see if things would settle down but I'm still sore , I've an appointment in March with the specialist nurse so will see if they change my Benepali

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There are several others available to try but it is a lottery which will work for you and unfortunately it may not be the first one you try. Have a look at the NRAS drug section before your appointment. For me Enbrel worked for 7 years then put on Humira for 9 months then tried Tocilizuimab - 4 months and Rituximab - one cycle followed by Abatacept which my 'one' for now.

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Lor’s experience ( healthunlocked.com/nras/pos... ) might be of interest, Wendy1973? 🤔 Very best wishes to you. 😌 🙏 🍀 🌺 🌞

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