I may be one of the unlucky ones but i was prescribed methotrexate four weeks ago and had a bad reaction to it. i was made stop take the medication as i experienced shortness of breath and chest pain pain.. i am also experience stomach pains like the worst indigestion you could get.. Has anyone else experienced this and is there anything that i could take to help with the stomach pain. I feel miserable.. My hair is also falling out.. i've lost quite a bit but luckily i have thick hair.. It is four weeks today since i took my first and last dose of methotrexate how long before it will be gone from my system?? and i will be back to feeling the way i use to.