This is an older research (2011) but it explains what MRI can show, how it works and makes interesting points that are still valid today.
msdiscovery.org/news/news_s...
The link includes a video of 24 MRI taken over 12 months on the same patient. It shows lesions appearing and disappearing (= a MRI/year can miss a lot of disease activity).
Just sharing as the report is one of the most readable I've seen. 2 points amongst many in the report:
- Brain lesions often don’t correlate with physical and cognitive symptoms. The discrepancy can partly be understood as a function of where in the nervous system those plaques hit, and of whether anatomical redundancies and adaptive mechanisms in a given person’s brain can compensate. (=our brain has lots of room to adapt)
- About Gd-enhanced lesions: Because the blood-brain barrier opens only temporarily in the early days to weeks of a lesion’s formation in MS, the dye can flow into, accumulate in, and highlight new plaques (active), but not old ones.