I have read that as you get older the DMTs no longer work. I brought this subject with my MS doctor at my last appointment and he looked at all my MRIs and spinal scans for the past 12 years and we decided I could try going off Copaxone which I have taken for 12 years at the end of this month. I will do a MRI in January and follow up with him in February. Has anyone gone off their DMTs and been successful? Anyone with bad reactions? I have RRMS.