Just a question

[Staroftheday]

hi sorry to ask am still getting my head around this I have ET and Jak2 am on pegsy 90mg weekly, will I always have this ? Also I feel like a pain in. My left arm the only way to describe it as if you have a blood pressure monitor on it goes tight then goes last night it woke me up felt like muscle twitching some times there a numb and buzzing In fingers any advice. Xx

[hunter5582]

Cytoreduction is a long-term treatment for ET. Hopefully you will find you can tolerate the PEG long-term. Many of us do well on it. Note that tolerance is dose-dependant.

The symptom you describe in your arm could be from the ET or from a PEG adverse effect. It sounds like one of several possibilities: paresthesia, peripheral neuropathy, some kind of microvascular symptom, or something else entirely. I would definitely not ignore this symptom. It would be advisable to let your care team know ASAP.

Please let us know how you get on.