Hi everyone as you can guess I am new to this site which was recommended by my consultant. I have been told I have pv with negative jak2. I have had 2 venesection a week apart , my next one is in 4 weeks. Reading through many posts I have gained more information than anywhere else so thank you. I will be honest I am a little scared of what it is exactly I am 45 and have 3 fantastic children my partner is as confused as I am . This has all come about from a mini stroke I had back in March this year. The tiredness is driving me nuts as are the headaches and feeling dizzy.. I do have one question what is the difference between being jak2 + and jak2 - can't seem to find an answer anywhere if someone could help please.