Indometacin: Has anyone tried... - National Migraine...

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Indometacin

Mary1959 profile image
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Has anyone tried Indometacin tablets as a preventative?

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Mary1959
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6 Replies
Wrexham16 profile image
Wrexham16

Hi. I took indomethacin years ago. It made my migraine much worse and also gave me ulceration throughout my digestive system and was advised to never take any NSAIDs again. But everyone is different!

Mary1959 profile image
Mary1959 in reply to Wrexham16

Thank you for your reply, think I'd better steer clear of that then, I already take medication for digestion problem 👍

e7seif profile image
e7seif

I've taken indomethacin suppositories (and a low dose of triptans), to treat my chronic migraines for years now. It works to stop the pain, but the pain does keep coming back daily for up to a week out of every month. I take omeprazole with it to protect my stomach, but I do worry about ulcers constantly. I would never take it as a preventative, but it can stop or reduce the pain of a bad attack, especially if you can't tolerate a full dose of triptans (like me). I wouldn't recommend it except as a last choice due to the ulcer danger. But if your pain is unresponsive to other meds, it can be worth asking your doctor about.

Mary1959 profile image
Mary1959 in reply to e7seif

Thankyou for your reply, I also take omeprazole, I'm like you, worried about stomach ulcers, don't want to replace one nightmare with another! At the moment, I'm on amitriptyline 3 at night, and got cocodamol and triptans to treat bad attacks. I try not to over medicate but sometimes, it's just a relief to get rid of the pain and just feel normal for a while. I'll chat with g.p when he rings thankyou and hope you're having a migraine free day x

troy04 profile image
troy04

Indomethacin is just another ibuprofen type pain killer and sometimes used as preventatives even though it creates a higher risk of having a heart attack or a stroke than people who do not take it. It can also cause ulcers just like ibuprofen if used regularly. However if a doctor is suggesting, they must have assessed these risks before prescribing.

Mary1959 profile image
Mary1959 in reply to troy04

Thank you for your reply Troy, I think I will stay clear of it, I already have problems with digedtion.