I have tried so many preventative treatments with no success so have just started in this treatment. Has anyone else been prescribed this?
my migraines are completely out of control at the moment 9 severe migraine days in the last 14 days so really hoping it helps.
Hi, love the name, ah I remember Jason Koumas very well!!!
I’ve been on Candesartan for many years now, it’s an ARB, angiotensin receptor blocker, it’s usually used for high blood pressure &/or heart failure. It isn’t officially approved for migraine use although there is evidence that it could help prevent them. As you’ve tried so many other preventatives it’s reasonable for your doctors to try this one out. It could just be the one for you, good luck.
You are going back a few years there with Koumas 😂. Thanks I’ve got everything crossed this one works.
Hi I trialled it back in January and gave up at 4mgs as thought it was making me worse but I was no better when I stopped it. I then tried Ajovy for 3 months but no luck as didn't help at all, gutted. I've just restarted Candesartan today to give it another trial as don't know what else to do. I suffer chronic daily migraines.
I too have tried Ajovy and Aimovig both did not make much difference to my migraines. Let’s hope candesartan helps us both.
It's depressing isn't it , especially when it can work wonders for other people. I wonder if you've tried Botox? I think I'll be offered it next
I’m trying the candesartan while I’m in the waiting list for Botox as the neurologist thinks that’s my best bet but there is quite a wait.
I had Candesartan but it made my blood pressure too low so I had to come off it. I've been on Ajovy for 2 years but the last year it's failed to work so I've cone off it. I'm waiting to try a different CGRP. Having migraines every day and stronger so I sympathize!
Hi Cat can I ask if you are trying a new CGRP via NHS or privately? I did Ajovy privately but got my long awaited NHS appointment soon and wondered if they will be able to offer me an alternative CGRP to try? Maybe it depends on where you live. I'm Greater London. Thanks
I’ve tried both ajovy and aimovig on the nhs. If you have a neurological centre near you you should be able to try it. I’m under the Walton Centre in Liverpool. In London you should be able to get it on the nhs.
I was with the nhs but once you get the funding you are on it for year. If the second CGRP fails I will go back to botox which for me was quite similar to CGRP. Even when they don't impact my frequency of migraine they still help the strength so it's still better than nothing. Have you tried botox?
I tried aimovig as well but similar results for me as ajovy. Hopefully you find something to work for you.
Yes I think if the next one doesn't work I'll have to go back to Botox bc the other CGRP's aren't good if you have IBS apparently, which I have.
Such a shame the CGRP gave me hope so gutted to be back here again!
I know I feel the same you hear of so many people that the CGRP medications have been life changing.
It sucks I think I'm on my 13 medication for migraines let alone my other conditions.
My neurologist said they might get better after the menopause so you never know?
Mine turned chronic after menopause 😫 but think I'm unique on that front as menopause helps most people!
I was always told years ago that menopause wouldn't make any difference. I've been chronic since my teens so maybe she's just trying to give me hope now that I'm 45!
I only had monthly period related migraine until menopause...now chronic for the last ten years...some of us are unlucky with menopause.
Did you try HRT for your migraines? Mine were also monthly and now constant post menopause
Hi...yes, I was on it till age 55... Then told I had to stop as not considered safe at that time .....so much negative publicity and so many scare stories. Doctor refused to let me continue.... Then the migraines became chronic and I was constantly told that they would settle and stop after menopause...but they didn't ......
My mother’s migraines got better after she had a hysterectomy. I can’t get anyone to do the surgery on me. If I do, my family doctor wants to assist. He thinks there will be a movie and he wants part of that. BTW, I’m a male. 😂😂😂 Good luck with your headaches. 👍🏻🙏🏻
I’m on Candesartan and topiramate at the moment. I can’t say I feel like it’s working for me but it may be the treatment that works for you. The neurologist said it has a high success rate when they put me on it and seem reluctant to change now.
Thanks for your reply if you don’t feel it’s working for you go back to your neurologist. I think this is my 8th preventative treatment I’ve tried so there’s plenty of options to try.
8 preventatives? Didn't think there were that many although if you include 2 x CGRP I guess it makes sense. Which were the others you tried? Thanks
I’ve had topiramate, amitriptyline, nortriptyline, propanol,Indomethacin and another I forget the name of. Quite a few the side effects were so bad I was only on them a few days. Also had a nerve block, tried a Cefaly device and had acupuncture.
I had a nerve block a few weeks ago, did nothing for me!
I've had Candesartan for many, many years too and Botox. I still get migraines very frequently and I'm in menopause. They are just not so intense. I wish you well and hope you find a solution that works for you. Just make sure you get blood tests for your kidney function if you take Candesartan long term. Mine are deteriorating because of it but I can't manage without it.
Thank you for your helpful reply. I am only in 4mg at the moment but feeling light headed, dizzy and nauseous hope it settles down.
Aww bless you. Can completely relate. Since April I’ve had nearly daily migraine attacks. I’m on Candasartan- I’m on 32mg now which is the max. It worked for me for quite a while. I’ve always tolerated them quite well. I’m waiting for the anti/CGRP injections which I’ve been prescribed but I’m still waiting for delivery. I think the Candasartan certainly has reduced the severity of them just not the frequency.
I really hope the anti CGRP injections work for you. It’s early days for me with candasartan I’m still trying to stay positive.
Hi yes I take candersatan have done for 3 years and it has helped so much do give it a try Kind Regards Ava
That’s great I’m pleased it has worked for you. 🤞 it works for me too.
YES!!! I have had migraines for over 50 years. I started Candesartan on January 14, 2014. Since then, I’ve had ONE bad headache where I vomited. It CHANGED my life!!! I hope you have similar success. 👍🏻👍🏻👍🏻
Wow that’s brilliant you must really feel you have your life back.
I was just given this, but unfortunately it makes me feel really nauseous and I feel anxious 
I've tried so many preventives too.
I felt like this for the first few days but it has settled down now. I’m only on the lowest dose due to increase it to 8mg this week.
I tried it for 2 weeks and I just felt worse, I had a break then tried it again the other day but the nausea just was too much. I too was told to increase it but I just don't see it working for me. Im glad it seems to be working for you.
That’s a shame for you. I hope you find something else that works for you.
I’ve tried all the usual preventative drugs and candesartan is the only one that’s worked for me. I still get them but much improved
That’s promising. I’ve gone up to 8mg this week so 🤞.
Have you had any improvement yet? I'm about to go up to 4mgs but no change so far. Thanks
Not too sure yet as I had an awful migraine just before I started it and that usually means my migraines settle down a bit. I don’t think I will see much difference until I’ve been on a higher dose for longer.
Have you increased every 2 weeks or gone up quicker? Also do you split your dosage morning and night or 8 mgs at once? Thanks
I increased to 8mg after about a week and a half. Been taking 8mg for a week now. I had no side effects when I increased the dose. I take the full 8mg usually in the afternoon. Got an appointment with the gp next week to discuss whether I need to increase the dose further.
Great thanks for the info. Has the early nausea and dizziness settled down now? I have both but hard to know if due to constant migraine or the drug
The nausea and dizziness settled down after about 4-5 days no side effects at all after that.
HiYes I take candesartan for migraines; 4 mg in the morning and I can take an extra 2 mg which I would take in the evening if needed. I have found an improvement as I do have less migraines. I keep a check on my blood pressure as it is normally normal but candesartan can lower it so have to take care with that. I hope it helps
I’m really pleased you have found something that helps with your migraines. My migraines seem to be a bit better but it’s early days yet. I will keep an eye on my blood pressure thanks.
Ahh I feel your pain 🥺🥺 I have been on candesartan for probably a year now and it has truly changed my life! After having migraines weekly (3days a week) I tried amitriptyline, propranolol, Topiramate, amitriptyline again max dose this time and then I went private and they told me to try candesartan started on 4mg then increased to 6mg and I stayed on that dose as it works wonders for me! And I have naturally low blood pressure so I was worried about being on this but I’m fine no side effects thankfully and I’m down to 1 migraine every 1-2 months and the severity is massively reduced! If anyone is taking triptans I’d highly recommend coming off them as I’m sure they made mine 100 x worse!! Stay positive please it is so important as although it hasn’t worked for others it has worked for so many and praying it works for you too ❤️ Let us know in a few months how you get on!!
That’s brilliant that it has made such a massive difference to your migraines. It must be wonderful to have your life back. Sounds like you have had a similar journey to me with the medications you have tried. I am up to 8mg now and it’s still early days but my migraines do seem to be a bit better.
I tried Candesartan several years ago. I could not continue with it as it lowered my BP too much. I hope it works for you. I have tried everything I think, even Botox, but nothing has helped apart from flunarizine, which has roughly halved the migraines ( from 20 to 10/12 monthly now). Maybe this is worth trying?
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