It takes 2-3 days for Warfarin/Coumad... - Hughes Syndrome A...

Hughes Syndrome APS Forum

10,356 members10,544 posts

It takes 2-3 days for Warfarin/Coumadin adjustments to affect my INR. How long does it take for a bowl of green vegetables to affect INR?

iwantsimple profile image
21 Replies
Written by
iwantsimple profile image
iwantsimple
To view profiles and participate in discussions please or .
21 Replies
Jade profile image
Jade

In my experience if eat broccoli with my evening meal, then by the morning my INR will have dropped.

I do know however this is because I do not eat the same amount each day as I think a diet like that is so boring.

Manofmendip profile image
Manofmendip

When I was on Warfarin, now on fragmin, 6 Brussells Sprouts would nock my INR down in about 12 - 18 hours.

Best wishes.

Dave

iwantsimple profile image
iwantsimple

That's what I was thinking. I thought if it took 3 days to go up, it might take 3 days to go down, but it seems like every time I eat something green, I feel the drop by the next day. I'm like Jade, and my diet tends to vary. I'm going to start self-monitoring soon, and that will help a lot. THANK YOU for the info!!!

iwantsimple profile image
iwantsimple

By the way, Dave...

As if anyone needed another reason NOT to eat brussell sprouts...YUCK!!!

LOL! :)

Molliesmom profile image
Molliesmom in reply to iwantsimple

they are good, steam them, slice in half, fry in butter till browned, add some salt and pepper and some shaker parmesan..tasty..lol

GinaD profile image
GinaD

I too have come to believe that a dietary Vitamin K intake beyond my usual amount will be felt about 12 - 18 hours later. And actually, I love Vitamin K veggies. And isn't it ironically unfair that someone who actually LIKES the taste of liver now can not eat it? (Vitamin K level is too high to even try to incorporate it into a diet.)]

Maye you've never tried roasted brussel sprouts? Make an X slit in the stem, remove outer leaves, roll about in seasoned olive oil and roast until soft. Hummmmmm.

chapman profile image
chapman in reply to GinaD

so as well as some green veg(witch i lv) and grape juice.liver is out aswell !? going to try ur roasted sprouts. thanks.stacey

Susiebelle profile image
Susiebelle in reply to GinaD

I love green however I am in hospital following a badly swollen & bruised thigh - all checked out ok but they checked my INR which turned out to be 4.

So Friday night was told to miss a dose & had vitamin K which I question - so agreed on a reduced amount - brought INR to 1.8.

Last night took 6 mg warfarin - INR had dropped to 1.1 this morning - so 8 mg this evening and another test tomorrow morning - this has me feel very jitterysince I had a stroke caused by AF ( which I still have). I only hope my INR is back within range tomorrow.

lovemyheart profile image
lovemyheart

:( i made myself a bowl of brussel sprouts the other day with butter sauce. I didnt know it could knock the inr like that. I hope having vwd balanced it

I am Lupus anticoagulant and have a selftesting machine.

I agree with Dave that it takes 12-18 hours before the INR goes down with vitamin K intake.

I do not think it is boring to keep that diet. I do not gain weight. I have no other alternative. Warfarin has changed my life and probably saved my life. I hope it will remain so.

k7pbx profile image
k7pbx

"For me", overnight to lower it. 12 hours to go from 3.0 to 1.6.

I was going to have a tooth removed and the dentist would not do it with out INR below 2.0.

Eating a pint of Broccoli.

It was for surgery. The INR clinic asked how I did it, and don't ever do it again.

To raise it back? Four days.

GinaD profile image
GinaD

This is controversial. When I went on warfarin back in the 80s for what we thought was thrombocytosis, I followed some atypical medical advice to take a varied warfarin doseage (alternating amounts on a 2 or 3 day cycle,) and incorporating green leafies with an eye to keep the 48 hourVitamin K intake the same.

I did so well on this unusual protocol that when I resumed warfarin therapy back in 2001 I asked to stay on my previous, unusual regimen. And I got provisional agreement, and now, 12 years later, I have been measured out of range only 3 times-- twice too low, once too high.

I know it's wierd but it works for me,

The doctor who originally (30 years ago) suggested the fluctuating doseage claimed that varying the dose keeps the body from compensating which would force me to take a higher dose. I have no idea if his rationale was, or is, accurate. But it works for me. And I am now very aware that this approach seems dangerous to many on this site, but so far, it works for me.

And though my hematologist is no fan of my approach, he acknowledges that my approach seems to work for me.

Gina

Susiebelle profile image
Susiebelle in reply to GinaD

Hi - exactly what do you mean by varying dose?

Thanks

GinaD profile image
GinaD in reply to Susiebelle

Since I wrote this post i have bern moved from a varying dose -which was 7.5mg one day to 10 mg the next --back toa more traditional daily dose.

And how quickly a meal of Vitamin K rich food will result in an INR change depends on the person. By Following this site for many years i note that some people see changes hours, and others days later.

Lure2 profile image
Lure2 in reply to Susiebelle

Hi Susiebelle,

We all have APS (Hughes Syndrome) here and we can be more sensitive to Warfarin than a "normal" patient on warfarin so it can be difficult to say how long time it takes to change the Warfarin INR if you do not have APS like us.

Are you diagnosed APS?

Best wishes from Kerstin in Stockholm

Susiebelle profile image
Susiebelle in reply to Lure2

No not diagnosed with APS

Lure2 profile image
Lure2 in reply to Susiebelle

Good! It should be easier when you do not have APS to stay steady on warfarin. Read about it.

Kerstin in Stockholm

Susiebelle profile image
Susiebelle in reply to Lure2

Thank you Kerstin

iwantsimple profile image
iwantsimple

Hmm.....that's really interesting. My docs do have me alternate dosages, too. They've had me doing 3 mg with a 4 mg thrown in every 2nd day or every 3rd day at different times. Nothing we've tried has been very effective. I wonder if my having had gastric bypass surgery has something to do with it. I'm not thinking that I'm absorbing the warfarin any differently than I should be but that the foods I eat are absorbed at different rates (or not at all), and diarrhea (which I've read can cause INR to drop drastically overnight) is a common problem at random times.

Hello K7pbx,

Dropping like that in INR must be dangerous. I do not know why you take warfarin but below 2 is a risk of stroke or DVT or something else. I can guess that you are not used to take green vegetables of vitamin K. I Always eat a Little bit of green vegetables but sometimes when my INR is to high (I use my Coaghushekmachine every morning) I eat a Little more broccoli or something with witamin K. My hospital knows about this and aproves it.

Susiebelle profile image
Susiebelle in reply to

I was given Vit K orally by the hospital -? A knee jerk reaction by them in hindsight

You may also like...