Preclinical: optimized delivery looks... - Fight Prostate Ca...

Fight Prostate Cancer

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Preclinical: optimized delivery looks very promising!

Maxone73 profile image
8 Replies

Delivery is one of the most critical factors. Whether we're dealing with a drug or a natural compound from a supplement, having the right 'ingredient' means nothing if we can't get it to the right place. Our body lives outside the controlled environment of a petri dish.

And now, we see another important step forward in overcoming that challenge...

A team of German and US researchers have developed a new gene-editing delivery system called ENVLPE that uses virus-like particles to transport fully assembled CRISPR-based editors into living cells more safely and efficiently.

Unlike older methods like AAVs or lipid nanoparticles, ENVLPE avoids immune reactions and delivers tools in their complete, protected form. In mouse models, it restored vision from inherited blindness using over 10 times less dose than competing systems.

The technology holds major promise for prostate cancer by enabling precise genetic edits and improving T cell engineering. Future developments aim to target specific tissues—potentially making prostate cancer treatments more effective, accessible, and customizable.

prostatewarriors.com/2025/0...

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Maxone73 profile image
Maxone73
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8 Replies
Broccoli24 profile image
Broccoli24

Ah, Max… you’re bringing so much hope, thank you!!

Maxone73 profile image
Maxone73 in reply toBroccoli24

I hope I won't disappoint...

Broccoli24 profile image
Broccoli24 in reply toMaxone73

You don’t! We just have to make sure we get further down the line to take advantage of this good news!

Maxone73 profile image
Maxone73 in reply toBroccoli24

I try my best and I try to stay positive and to transfer positiveness, but today's news about fallen warriors hit me

Peppertree602 profile image
Peppertree602

as always Max our number 1 researcher!

Don717 profile image
Don717

You do an excellent job Max....I hope they pay you well!! 😆

Maxone73 profile image
Maxone73 in reply toDon717

I just want the big prize as payment!!!

Don717 profile image
Don717 in reply toMaxone73

I hear ya...and I hope you get it!

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