The Cancer Some Doctors No Longer Want To Call Cancer (Prostate). Sumathi Reddy is the author of the story in the Wall Street Journal.

[Baldylocks]

Has anyone heard or read this story and can you tell us what’s going on? I don’t subscribe to the WSJ so I only saw the headline but no story.

[Izzygirl1]

I want to read that too!

[Baldylocks in reply to Izzygirl1]

If I remember I’ll look for that edition at the newsstand tomorrow and give more details.

[Steel67]

it’s for those with the lowest grade curable cancer - renaming it would lead to less aggressive/ more appropriate treatments

[Baldylocks in reply to Steel67]

how do they make that determination prior to mapping a treatment plan?

[addicted2cycling]

Baldylocks wrote -- " how do they make that determination prior to mapping a treatment plan? "

Biopsy + scans + available testing ???

Gleason 6 Prostate Cancer: Serious Malignancy or Toothless Lion?

January 15, 2014

Herbert Lepor, MD

Nicholas M. Donin, MD

>>> cancernetwork.com/view/glea...

" Conclusion

The preponderance of evidence suggests that true pathologic Gleason 6 disease, while possessing the ability to grow and extend locally, has an exceedingly low, if any, metastatic potential. Therefore, it is our opinion that today’s pathologic Gleason 6 disease should not be labeled as a cancer. However, it remains to be determined whether Gleason 6 disease has the capacity over time to transform and acquire a metastatic phenotype, and as such, we do believe this entity should be differentiated from benign entities. Unfortunately, we can confidently diagnose true Gleason 6 disease only after the prostate has been removed. The future lies in developing a new paradigm for screening and detecting prostate cancers that uses imaging and molecular tools to selectively identify only cancers with a metastatic phenotype. "

10 years later and acceptance of above evidently is growing due to the increase in Active Surveillance

[KocoPr in reply to addicted2cycling]

I was gleason 6 with onlr 1% of one out of twelve cores. Put on active waiting then active surveillance which lasted 2 years and would have continued but i did a lot of my own genetic research based on 23amdme (which now has fda approval for some genes) .

I have a rare FGFR4 mutation and according to research predicts 6x chance of getting metastatic prostate cancer and 5.3 x chance of it becoming aggressive. I demanded to have my prostate taken out. I was upgraded to gleason 7 with perinueral invasion and cancer had escaped in two locations.

Presently 11 1/2 years later i keep the beast fed every two weeks with super high testosterone and nail the beast every other two weeks with darolutamide.

Needless to say I would probably be dead by know if I didn’t have prostatectomy in 2015.

[KocoPr in reply to KocoPr]

I don’t trust WSJ for managing my health choices as they are heavily invested in stock market (corporate profits). I certainly don’t trust their biased opinion pieces.

[addicted2cycling in reply to KocoPr]

I'm a 2015 Gleason 10 with half a prostate cryoablated and half left. PSMA PET/CT just showed uptake in left, NOTHING in right AND in 2 weeks from this morning my 3D Prostate MAPPING Biopsy will be completed and results to come. Not really concerned.

[KocoPr in reply to addicted2cycling]

It only pertains to gleason 6 being categorized as not having cancer. Certainly a more robust detection process like liquid biopsy, circulating tumor cells, better real time imaging , germline genetics, guided biopsy would be in store if they were thinking of telling Gleason 6 patients “nothing to worry about you don’t have cancer”

[Baldylocks in reply to KocoPr]

isn’t this the argument why not to remove prostate measures at any level from cancer studies and treatment plans? what of the so-called odd man out that doesn’t get treatment and ends up with a metastasis? what’s to be told him?

[groundhogy]

Ok i have heard this before and i can not understand it. That gleason 3 is not a risk and it will never hurt you and that patients should just leave it be and go watch TV.

So... how does gleason 5 occur? Does it spontaneously appear without first being gleason 1,2,3, or 4?

From what i have read, cancer mutates and morphs rapidly. It becomes stronger, more able to survive as it goes.

I already have trust issues with this industry. If i had gleason 3+3, and a glad-handing doctor, i would not rest well.

[Baldylocks]

I don’t have the answer comrade but I’m sure we’ll hear more on this sooner than later.