Janumet drug concerns

[Concernedguy]

Is taking Janumet 50/500 safe? How long have you guys been taking it? Have you faced any side effects?

[Activity2004 Administrator]

Hi and welcome to the group.😀👍

Have you talked with your doctor about your concerns about the Janumet 50/500? When was your last appointment with your doctor? What is your A1c from your last blood drawing?

[gangadharan_nair]

Janumet consists of two drug combination of Metformin (500 mg) + Sitagliptin (50 mg).

Metformin is used alone or with other medications, including insulin, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Metformin is in a class of drugs called biguanides. Metformin helps to control the amount of glucose (sugar) in your blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. Metformin also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood.

Sitagliptin is used along with diet and exercise and sometimes with other medications to lower blood sugar levels in patients with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Sitagliptin is in a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the amounts of certain natural substances that lower blood sugar when it is high.

Major & minor side effects for Janumet (500/50 mg) Tablet

Anxiety

(severe)

Chills

(severe)

Blurred vision

(severe)

Confusion

(severe)

Cough

Fever

Sore throat

Nausea and vomiting

Diarrhea

Abdominal pain

Hypoglycemia

(severe)

Lactic Acidosis

(severe)

Weakness

Chest discomfort

Headache

Runny Nose

Belching and Heartburn

Swollen joints

(rare)

Links:-

en.wikipedia.org/wiki/Metfo...

medlineplus.gov/druginfo/me...

en.wikipedia.org/wiki/Sitag...

medlineplus.gov/druginfo/me...

[sandybrown]

Any medication questions need to be put to a doctor!

Different medication reacts differently with different human.

Please think about this.

Type of medication, dosage, when and how to take it, only a specialist can answer it.

Take a look at this link:

webmd.com/drugs/2/drug-1480...

[Concernedguy]

Hi All Thanks for all the comments, I have been able to keep my sugar levels under control by using this in conjunction with the diet and exercise.

But read about increased risk of pancreas using this medicine, few many cases reported some years back in US.

ncbi.nlm.nih.gov/pubmed/265...

litigationandtrial.com/janu...

fda.gov/downloads/Drugs/Dru...

Hence wanted to ask the and get some few thoughts in this aspect.

[sandybrown in reply to Concernedguy]

Try and enjoy one life. Stop worrying!!

Even professors medical, medical doctors do get cancer, have operation and look forward to better life!!

Most medication have side effect.

This is from the Internet: "The study found six genes clearly linked to an increased risk of pancreatic cancer: BRCA1, BRCA2, CDKN2A, TP53, MLH1 and ATM. ... Patients who have these genetic mutations are at a substantially higher risk for pancreatic cancer, but that does not definitively mean they will develop the disease.".

You could go for tests but is it necessary? I believe in this my mum gave me a number of heart beat when she gave me life. I am 72, I do not know when this time is, for mum some one gave her time, 7 days after my brothers birth. Yes it happened.

All my life I did all I want to do with my family, like the song " I did it my way!"

If you are taking medication, take it, enjoy life.

[sandybrown in reply to Concernedguy]

Have a look at this report:

dailymail.co.uk/health/arti...