Anyone know what the MOST causative element to dyskinesia is? Is it the duration of the Rx? Is it related to the dosage of the Rx?
I'm headed back to the neuro and I'm not sure if he's going to suggest an increased dosage or a different medication. I would obviously like to prolong the onset of dyskinesia as long as possible.
My take is it is probably both. However, since everyone is so different it is probably difficult to give a definitive answer.
What does Rx mean please?
Sorry, Rx is short hand for "prescription" or medication
I suspect that this is a term used only in the USA. or I've missed it for years and years.
My understanding is that dyskinesa starts after a number of years taking Levodopa in whatever form but that if you overdose on Levodopa then you may get dyskinesia as a consequence. Not permanently though. And the number of years is not possible to predict for any individual.
I'm glad someone has already asked what Rx means because to me Rx means receive and the counterpart Tx mean transmit. I was left wondering what Rx could conceivably mean in a PD context.
It's a pretty common abbreviation here in the states. As an amateur radio operator (HAM) I am also familiar with the "receive" connection. Sorry for the confusion.
I had dyskinesa withing my first year of diagnosis. It went away immediately the doctor prescribed a lower strength of sinemet.
I agree with Pete-1 to a point. Taking Levocarb over a long period of time seems to cause dyskinesa for what reason I do not know. It may happen after a longer period for ssome people andd a shorteer time for others. Why? Your guess isas good as mine. When I go to a doctor and get a prescriptopn, RX iss always oon the paper .
Last year we held a PD conference, and Dr. Erik Alskog presented. He stated that there is a relationship between dosage and age. To reduce dyskinesia, reduce Levo/Carb. At the same time the relationship with age is the opposite of what one might think. The percentage of those with PD who experience dyskinesia is greater for those who are younger. 50% of those aged 40 to 59 years will experience dyskinesia, whereas 26% of 60 - 69 year olds and 16% of 70 - 79 and only 14% of those aged 80 - 89 have dyskinesia.
Toadma, thanks! That's exactly the info I was looking for. Of course, much like MS I know that PD effects everyone differently but it helps start a conversation with my neuro. Thanks again for the info.
Aggiebiker
I dont think they fully understand dyskinesia yet but it is a factor of age, length of time on LDopa and dose strength. In the early days of L Dopa treatment people took very high doses and developed severe dyskenesia. Now mostly our dose is much better controlled and there are far less problems but I think we are still living with the fear from those earlier days.
There is another factor too that could be important and that is giving our brains an even amount of LDopa so being consistent with medication. The fluctuations during the day may have a long term effect on the brain. Thats also why i have always thought going on and off medication too often may increase the chance of developing dyskinesia.
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