SLEEP WITH PD is very different to NORMAL PATIENT, WHY??

[professor]

COMPARING ELECTROLYTE( spinal fluids) when sleeping,THE HORMONE/ FLUID. quantity /pressure COULD ESTABLISH,THE MISSING

ELEMENTS. why parkys dont sleep, and might give an indicator to find a cure

THIS is a worthwhile sensible and valueable experiment,

COMMENTS PLEASE

[Balderdash]

My sleep pattern did not become disordered until, I started medication Perhaps brain chemistry altered by medication is more responsible in this instance than PD itself .Disordered in the sense that I rarely sleep more than 4 to 6hrs, sometimes as little as 3 hours having been a 7 to 8 hour person.My PD symptoms are worse with lack of sleep and much improved with a regimented sleep pattern rather than the irregular one PD and meds would let me haveThe iron lady margaret thatcher used to boast about needing 4hrs sleep each night she now has dementia.A link perhaps.

Current research reveals links but not causes

Marker for Alzheimer’s disease rises during day, falls with sleep.

“In healthy people, levels of amyloid beta drop to their lowest point about six hours after sleep, and return to their highest point six hours after maximum wakefulness, sleep and wakefulness were the only phenomena that strongly correlated with the rise and fall of amyloid beta in the spinal fluid.”

news.wustl.edu/news/Pages/2...

It was observed that in patients who had raised CSF pressure that there is a breakdown of the cyclic sleep pattern with increased duration of light sleep and higher number of awakening episodes, and with reduced amount of deep sleep and nearly complete absence of REM sleep.

ncbi.nlm.nih.gov/pubmed/714...

(Ivanhoe Newswire) -- A rare sleep disorder that causes people to fall asleep suddenly during the day may partly be explained by low levels of a key substance in the cerebral spinal fluid (CSF).

Researchers who studied people with narcolepsy find those who also suffer from cataplexy -- a temporary decrease or even complete loss of muscle control -- are more likely to have low hypocretin-1 levels in their CSF. Hypocretin-1 is a protein known to play a role in regulating our ability to sleep and wake.

[moonswife]

Balderdash raised excellent points with valid references.

I offer a slightly different perspective. My husband has a pill schedule at night that has the alarms ring at 9 at 10, at 2 and 6.

Mike drinks a full bottle of water with each batch of pills. So he pees at least that often. He never feels he needs to when he takes the pills, but when he lays back down, rolls over on his stomach (and bladder) the fullness sends him running (tongue in cheek, it sends him shuffling at a very fast pace) For him maybe a simple, but different answer to your question.

[PatV in reply to moonswife]

I have 'visceral off' so I almost CAN'T pee until meds kick in. Then watch out.