Possible autoimmune arthritis, with Sjögren’s like symptoms,affected by eating gluten/ too much sugar

[Smartdoc2]

Hello any body out there with several symptoms suggesting Sjögren’s syndrome + inflammation of joints that is seronegative ,and finds that eating gluten makes both pd and autoimmune conditions worse?

[Boscoejean]

"Research indicates a significant link between Parkinson's disease and Sjögren's syndrome, with studies showing that individuals diagnosed with Sjögren's syndrome have a considerably higher risk of developing Parkinson's disease, particularly among women and younger patients; this association is likely due to the shared autoimmune nature of both conditions.

Key points about the connection:

Increased risk:

Studies consistently demonstrate that people with Sjögren's syndrome have a higher likelihood of developing Parkinson's disease compared to the general population.

Autoimmune basis:

Both conditions are considered autoimmune diseases, where the body's immune system attacks healthy tissues, potentially explaining the link between them.

Mechanism not fully understood:

While the exact mechanism is still being researched, theories suggest that shared immune system dysregulation in Sjögren's might contribute to the development of Parkinson's.

Important considerations:

Not everyone with Sjögren's develops Parkinson's:

While the risk is elevated, not all individuals with Sjögren's syndrome will develop Parkinson's disease."

Early detection is crucial:

If you have Sjögren's syndrome, it's important to be aware of potential Parkinson's symptoms and consult a healthcare professional if you notice any concerning changes.

[Boscoejean]

"gluten can make Sjogren's syndrome worse because it can trigger inflammation. Some people with Sjogren's syndrome also have celiac disease and should avoid gluten.

Explanation

Gluten can trigger inflammation that worsens Sjogren's symptoms.

Some people with Sjogren's syndrome have celiac disease, and eating gluten can harm them.

A gluten-free diet may help alleviate symptoms for people with both Sjogren's and celiac disease.

Other Sjogren's diet tips:

Avoid foods that are spicy, hard, crunchy, or acidic

Avoid red meat, processed foods, and fried foods

Avoid refined grains, safflower, corn, and canola oils

Avoid alcohol, soda, and artificial sweeteners and preservatives

Additional Sjogren's treatments: Use eye lubricants daily, Sleep with special eye gels, Use warm compresses daily, Brush your teeth after each meal, and Use a room humidifier.

If you're concerned that dryness may represent Sjogren's syndrome, see a rheumatologist. "

[MarionP in reply to Boscoejean]

I mentioned below response to Smartdoc and below here the additional similar effect of antihistamines which is widespread. Use of antihistamines as widespread and one doesn't need to have antibodies (necessarily), and I know of cases of people with chronic sugar allergies for instance creating chronic pruritus for which constant antihistamines are required. Antihistamines dry you out and because of the dring out produce a lot of those symptoms, and having a chronic allergy also means those nerves have been damaged long long ago and maybe now hypersensitive and hyper-inflamed... That's the same as that beef sugar allergy you read about. And allergies of course are autoimmune diseases. Then there are all those new medications for eczema and extreme psoriasis and the light, you see those ads all the time, and every one of those has a mechanism of the specifically shutting off or interfering with one or more autoimmune mechanisms, which is why they all have such serious warnings about getting infections, because they shut off various interleukin pathways and processes from occurring, thus exposing people to infections, basically the infections can be much worse because you have shut off the particular parts of your immune system that protect you and fight those infections. We recently had a conversation about the famous Jordan Peterson and what chronic overuse of benzo diazepines did to his nerve system, well that's the same process I'm describing above with regard to antihistamines, they can eventually result in something similar or you have damage to portions of the nerve and the damage becomes permanent and and you become hypersensitive with the opposite sorts of rebound reactions and nerves that inflame on their own... I like in it too haven't had too much electricity go through those nervous systems and kind of screw with them after that, some of the damage is permanent. In fact, one very early drug used to control hives was also used to control anxiety, it was called Atarax (hydroxyzine) and it is basically an antihistamine but it has to be prescribed... and it is a chemical cousin of thorazine. Today there is an over-the-counter second generation of hydroxyzine, which is the antihistamine called Zyrtec (cetirizine), same stuff except it doesn't make you drowsy...and it is used for exactly those purposes, namely skin allergies, itching, hives. Change the shape of the molecule or add a couple of different atoms here or there and you have the very powerful antipsychotic thorazine.

[Kruidje in reply to Boscoejean]

For my auto-immuuncondition I practice all the above avoiding tips. Accept for unproccessed red meat. Almost half of my diet is red meat, the other part is animal fats like tallow, goosefat or duckfat. And it works very fine. Togheter with adding supps like thiamine, and some of the other b-vitamines, aminoacid's, minerals and some from time to time some binders. If I eat graines (with or without gluten) or fruits or vegies or legumes I fell of the wagon and my auto-immuuncondition (more symptoms for hashimoto, eds, parkinson, sjorgen, depression) become worse.

[Boscoejean]

"Seronegative Sjögren's syndrome is a form of Sjögren's syndrome, an autoimmune disorder that primarily affects the moisture-producing glands (salivary and lacrimal). Unlike seropositive Sjögren's syndrome, seronegative patients do not have detectable antibodies (anti-Ro/SSA and anti-La/SSB) in their blood.

Symptoms:

Seronegative Sjögren's syndrome typically presents with similar symptoms to seropositive Sjögren's syndrome, including:

Dry mouth (xerostomia)

Dry eyes (keratoconjunctivitis sicca)

Fatigue

Joint pain

Vaginal dryness

Raynaud's phenomenon

Oral ulcers

Dental caries

Diagnosis:

Diagnosing seronegative Sjögren's syndrome can be challenging as there are no specific diagnostic antibodies. The diagnosis is typically based on clinical symptoms and a positive lip biopsy, which shows inflammation and damage to the salivary glands. Other diagnostic tests may include:

Blood tests to rule out other conditions, Salivary flow rate measurement, Tear production test, and Ophthalmological exam. "

[MarionP]

For seronegative, or even perhaps both varieties, one might have to rule out and control for people who have long-term use of antihistamines or anticholinergic medication (because both dry out moisture producing tissues). Or perhaps one could have both conditions exacerbating each other, of Sjögren's syndrome and drying out from antihistamine medication. I guess you would call it a differential diagnosis question.

So for us non-doctors, for instance widespread use of antihistamines to control chronic allergies (allergies are immune conditions by definition), and their drying out of salivary glands, naturally expose those glands to infection from bacteria, perhaps those typically found in the mouth (including tooth decay and bacteria migrating up the salivary glands and creating infection). Bacteria can migrate up those tracts and colonize (infect). Similarly, dry eyes are what happens when antihistamines are used in eyes or systemic antihistamines are used. Reynauds is narrowing of small arteries in toes and fingers, which is something imposed by antihistamines and any other vasoconstrictors that affect those blood vessels, perhaps combined with the nerves that constrict those arteries' failure to relax and dilate those arteries back.