These new scientific fraud cases worry me: Now also in material science - Sabine Hossenfelder youtu.be/EpQobaBCSYk?si=sZ3...
Correction to what I say at 01:56 -- He had 35 papers retracted, not 65, sorry about that. I mixed up the numbers. (Bad enough as it is!)
I’ve talked a lot about scientific fraud in the past. Now, investigations have found even more widespread examples of falsified research. Not just in psychology and medicine, but also in material science. Let’s take a look.
Sabine is guilty of exaggeration - well known that curcumin is poorly absorbed. Bioavailabilty can be increased considerably using black pepper extract. Regarding Aggarwal - here is a 2021 review paper of curcumin and Parkinson's. They list 161 references, of which only six involve Aggarwal: mdpi.com/1422-0067/22/20/11248
Yes no-one has time for proper peer review. The recent allegations in Science against MasLiah are shocking - he coauthored more than 300 papers on alpha-synuclein which together have more than 30,000 citations. I went through the list of references to that recent Nature paper on prasinezumab and his name was not there but it occurred explicitly 3 times in the major background reference they used and I am sure that his papers will be cited by other papers in their list. His wikipedia page is now pretty damning about him. I had read about Aggarwal a while ago (I heard her say 65!). It put me off curcumin. When papers are retracted the review articles that summarise them and draw their conclusions from them, do not change even when directly requested to do so! The health influencers flash up research papers (they like reviews) like confetti without knowing their quality or reliability - something you only really know if you are active in the field yourself.
You may want to take a look at my habitual favorite tracker, Retractions.org, as well. Never any exaggeration, always extremely careful and demonstrable, very high standards. And the problem isn't alone with time for proper peer review, it's fraudulent peer review, peer review that has been substantially hidden, failure of peer review to pay sufficient attention to research integrity, failure to punish research integrity breaches (particularly those that are intentional), and failure to make retractions, in other words, the dishonesty is not just with the peer review process, but with publishers and it is a widespread widespread (did I mention WIDESPREAD?) problem. It's the Wild West all over out there.
She's humorous. I stopped taking Tumeric. I've never ever felt any benefit from it after several years of use. Most recently taking a version from Dr. Wahls, a source I trust. I subscribed to Ground News.
Most curcumin is poorly absorbed but but has limited cellular bioavailability.. Nano-formulations with micellular delivery have are 200 to 500X greater bioavailability and demonstrable effects. This provides neurological ameliorations both in experimental animals (doi.org/10.1016/j.neurophar... and in clinical trials, including neurological conditions (pubmed.ncbi.nlm.nih.gov/366... ). There have been several "promising" studies of PD, but they must be discounted since nano-curcumin in micelles was not used. That formulation (Flexofytol) is available from Cocooncenter in the UK at half the cost of its US distributors (vip.cocooncenter.co.uk/tilm... .
I went on curcumin for a while for mild knee arthritis. We have 2 local pharmacies and I asked both pharmacists which brand(s) had evidence of absorption/effect. The pharmacists were well aware of what is absorbed (or not). One advised only one product and the other suggested that same product or one other. Now despite this being a thread about fraud I would suggest that you treat your pharmacist as a professional and get their opinion. A good pharmacist will even look this stuff up for you which is a lot easier than doing it yourself.
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