There is a new medication called produodopa.
there was a video of a man who has pd, and it showed How he was before medication and after medication- the results were simply incredible.
Is anyone else on this medication, and do you have the same positive response? this should be available for everyone….
The drug is a rehashed levodopa as liquid, nothing incredible. The delivery is via a continuous pump into the skin so reducing off time.
I hear hospital roll out is slow, nurse resource time means they can only do one a week.
Is it similar to the appo pump
AI saysThe Appo pump and Produodopa are both used to treat Parkinson's disease, but they differ in several ways, including:
Medication
The Appo pump releases a combination of medications, while Produodopa is a combination of two drugs.
Indication
The Appo pump is used to treat motor fluctuations in patients whose Parkinson's disease is not well controlled by oral medication. Produodopa is used to treat advanced Parkinson's disease with severe motor fluctuations.
Side effects
The Appo pump can cause orange sweat, urine, and saliva, nausea or vomiting, and low blood pressure. Produodopa carries a small risk of infection due to the plastic tube that is inserted under the skin.
Dosage
The Appo pump's continuous infusion starts at 1mg per hour of apomorphine hydrochloride, and is increased based on the patient's response. Produodopa's maximum recommended daily dose is 6000 mg.
this is available in the UK for everyone (I think).
Have enquired about it for my HWP but we felt it was for very advanced Parkinson’s.
It is a pump that goes via a subcutaneous wire into the stomach.
Ask your Neurologist. Good luck
As described below.
Current UK criteria for eligibility is
Tried other methods either DBS assessment or apomorphine infusion.
But exceptions remain (especially if there are specific criteria for not tryin the above first)
Slow roll out is because of pricing ( £ 31,000 per year) as well as lack of enough data on dosing.
Understandable given the variance between individual symptoms and responses to oral treatments.
* data limitations : putting it into perspective
When insulin pumps were introduced 25 + years ago (nearly 8 decades after soluble insulin was available ) they had data from subcutaneous individual dosing from several million diabetics per country.
PWP represent less than a tenth of those numbers, and those severe enough to need it are likely to be 1% of the insulin diabetic population
Don't see a video What did it do 4 him?
youtube.com/shorts/x2hGO0HZC4g
Incredible. This should be made available to every pd sufferer…:
I met someone in US trial. She said it was a gamechanger. Total c/l cut in half, able to function all day.
Avail in Canada now
I have just been approved for the Appo pump and the drug Vyalev, a brand name for AbbVie's ABBV-951 (foslevodopa/foscarbidopa), The company felt that it would really help me and they will be sending out a nurse to our home to train us in how to use it. My husband needs to be trained in it as well so if I have trouble than he can help and if for some reason I end up in the hospital or unable to explain what I am hooked up to he can tell them and show them what needs to be done, I am in Canada and I believe that I am probably in the very first group on pd patients getting this, It is going to cost my insurance around $40,000 per year. And they approved it under a special program. I was told that I will not be set up with it until they can guarantee a supply of the drug because they are having trouble getting enough made because the demand is so high. that is apparently what is causing the slow rollout,
I will try to remember to come back and report on how it works for me.
Yes for sure report back...
Inquiry regarding ABBV-951 -Produodopa available for patients in US with Parkinson's Disease under the Right to Try/Compassionate Use
Medications for Parkinson's
How to find the right medication ?
Parkinsons and Osteoporosis medications
Requested help for further training of neurologist
