Hello all,
A friend with Parkinson’s has alerted me to a study wherein Rotenone-infected mice responded positively to Ecklonia Cava Polyphenols. See pubmed.ncbi.nlm.nih.gov/389...
Does anyone have experience of the efficacy of this polyphenol for managing PD symptoms?
This is a duplicate of the preceding post. This compound does not work for treating Parkinson's as explained there.
Oops sorry, I did do a search first but obviously missed it. Either that or the search function is case sensitive.
Bear, you clearly have a different view to many PD researchers as to the value of testing molecules on small mammals that have been "infected" with rotenone. Which is fine, but the supposed remedy is cheap so I will be trialing it just in case it is effective ...
I will revert if any positive to report.
I am in the prodromal phase and have added to my supplements. I found it to be safe until otherwise.
If they're allowed to actually develop Parkinson's motor impairments first, as will happen eventually after rotenone intoxication, then it would be a valid trial. Those who stoop to pretreatment before toxicant type studies do not merit being referred to as "Parkinson's researchers". healthunlocked.com/cure-par...
Compare to cinnamon, which actually works: healthunlocked.com/cure-par...
link.springer.com/article/1...
"The present investigation underlines the importance of a naturally used spice and flavoring agent viz. cinnamon in reducing α-syn deposits in transgenic mice expressing mutant A53T human α-syn. Upon oral administration, cinnamon markedly reduced the level of insoluble α-syn in nigra, hippocampus and brain stem of A53T mice..... In addition, both cinnamon and NaB treatments showed improvement in their motor and cognitive functions. "
Thanks Bear and yes, agree with your comments and use Cinnamon. Do you take the Ceylonese variant?
Yes, the Ceylon version is a must! The other variety of cinnamon, cassia cinnamon, contains coumarin, a blood thinner. This is a problem at the recommended dosage. If you have not already read my report at the second link above, please do so.
Well you know artificial construction of the illness is a pretty weak, almost useless experiment... it has a great deal of automatic self-destruct built into it.
.
On another hand, if you take something, and your symptoms improve, that's as good as anybody has been able to achieve. And maybe that's Parkinson's and maybe it isn't, but do you need to care at that point?
Either way I think I would get off of that and on to that cinnamon Park bear is talking about! Assuming that what I get is really cinnamon and not some adulterant. There's a lot of cinnamon bark consumed in the world, are there enough trees for the worldwide demand? That's why people add lead to saffron before selling it. Is there such a thing as pharmaceutical grade cinnamon?
No special grades as far as I know. So far I've been okay with the Frontier brand I've bought from Amazon.
Thanks very much. I seem to remember there's also a difference in the cinnamon you want, "there is cinnamon and then there is cinnamon." I think you've mentioned it before but as a "member," I don't have the kind of addressable personal library here on HU I really would like to have for accumulated critical bits of diamond. There are times when I wish HU would provide a website feature that lets individuals place a bookmark or library star on a particular entry and build an member's corresponding addressable "library" file or simple database in the person's own member space so they can consult it like their own index or library of really valuable special how-to's. Thus I would put PB's last response in my own personal library, which, having been critically filtered and vetted by me, could immediately be regarded by me as immediately trustworthy and actionable. There are far too many entries and comments and responses to be able to index and save those things that way in a productive manner for people. A simple bookmark function with the library then put in the person's own area would conserve this critical, filtered info of solutions, and increase the value to end users very significantly I think. Wouldn't take a website manager but a few minutes to set up and I don't think it would mess with their storage capacity much if at all. I wonder if they monitor these responses because this one little feature would be a game changer and who knows perhaps reflected in people's survey results and satisfaction surveys as well as perhaps creating a marketable addressable critical information library they could sell to suppliers, investigators, information brokers, merchants, de-identified perhaps but enough so to monetize the benefits both for website and turn value toward the end users and intermediate users and perhaps a very meaningful way. I've been on this website for what, years and years and I can't go searching and dealing with what I personally would love to do with each of the very special items I've noticed over the years, it would be just too clunky and I would not be able to reproduce the ideas and strategies and valuable bits especially since as a person with Parkinson's my cognition is declining every day... But as a psychologist I can certainly attest to the fact that recall fades well before recognition, thus even while cognition declines often a person can still recognize critical information they have seen when they are given a trigger, whereas recall is just too complex and degraded a function later on in the process, but a person's ability to recognize something lasts a person far longer. Boy would it ever have solved a lot of problems and who knows perhaps even made this website valuable enough to sell a subscription from to various types of users, more than is the case now I mean. There's a lot of value in any case to be unlocked by a really thoughtful response to this problem which I have often wondered about figuring out how to solve. What a simple easy solution my idea might incur.. I retired quite a while ago now so the last big database program I was familiar with was SQL, and I know it would be very easy to add this into an SQL base. There have to be many far easier and more functional systems available now in the market to HU. Maybe the "save entry" function could serve that purpose but I don't know and I don't really think it's what I had in mind, it needs also to be searchable and let me label it as I would care to, I eat find personally functional. How do I get HU's attention? "Report" my own entry perhaps? Where's a moderator when you need one?
Thanks very much. I seem to remember there's also a difference in the cinnamon you want, "there is cinnamon and then there is cinnamon." I think you've mentioned it before but as a "member," I don't have the kind of addressable personal library here on HU I really would like to have for accumulated critical bits of diamond. There are times when I wish HU would provide a website feature that lets individuals place a bookmark or library star on a particular entry and build an member's corresponding addressable "library" file or simple database in the person's own member space so they can consult it like their own index or library of really valuable special how-to's. Thus I would put PB's last response in my own personal library, which, having been critically filtered and vetted by me, could immediately be regarded by me as immediately trustworthy and actionable. There are far too many entries and comments and responses to be able to index and save those things that way in a productive manner for people. A simple bookmark function with the library then put in the person's own area would conserve this critical, filtered info of solutions, and increase the value to end users very significantly I think. Wouldn't take a website manager but a few minutes to set up and I don't think it would mess with their storage capacity much if at all. I wonder if they monitor these responses because this one little feature would be a game changer and who knows perhaps reflected in people's survey results and satisfaction surveys as well as perhaps creating a marketable addressable critical information library they could sell to suppliers, investigators, information brokers, merchants, de-identified perhaps but enough so to monetize the benefits both for website and turn value toward the end users and intermediate users and perhaps a very meaningful way. I've been on this website for what, years and years and I can't go searching and dealing with what I personally would love to do with each of the very special items I've noticed over the years, it would be just too clunky and I would not be able to reproduce the ideas and strategies and valuable bits especially since as a person with Parkinson's my cognition is declining every day... But as a psychologist I can certainly attest to the fact that recall fades well before recognition, thus even while cognition declines often a person can still recognize critical information they have seen when they are given a trigger, whereas recall is just too complex and degraded a function later on in the process, but a person's ability to recognize something lasts a person far longer. Boy would it ever have solved a lot of problems and who knows perhaps even made this website valuable enough to sell a subscription from to various types of users, more than is the case now I mean. There's a lot of value in any case to be unlocked by a really thoughtful response to this problem which I have often wondered about figuring out how to solve. What a simple easy solution my idea might incur.. I retired quite a while ago now so the last big database program I was familiar with was SQL, and I know it would be very easy to add this into an SQL base. There have to be many far easier and more functional systems available now in the market to HU. How do I get HU's attention? "Report" my own entry perhaps? Where's a moderator when you need one?
We can do what it is I believe you are seeking. If you click on "save post" underneath the desired post, it is then appended to your list of saved posts. You can access this list via the Health Unlocked "home" button at the upper left hand corner of the page.
Nope, not really. And that's not functional enough anyway. And what I am talking about is something extremely simple to accomplish and implement, while eliminating potential obstacles and likely obstacles easily. There are no good reasons to say no to the idea. None. And additionally, it's trigger could easily be placed in the "more" menu, but even then that's an obscurance, quite against the point I am making, which is to make it easier not harder, your steps not more steps, out in the open instead of something you have to first de-symbolize a symbol or avatar, imagine and reason and consider and separate from other things, and hold in your mind and memory, going back and forth mentally in order to realize where you are inside of a matrix... all of what you must be able to do with a system that is like the one we have, but which may be increasingly difficult for anybody to use. And what I am after is an immediate obvious prompt in any case, that presents itself when the mental need for it occurs. Like I said, recognition over recall, and simple over having to perform multiple simultaneous and sequential sorting and filtering functions in one's head, which is what you lose as natural aging and dementia and distractions such as bodily pain medication effects etc. encroach in any case. It would be nice if it instead of having just simply a webmaster, you had a webmaster who knows a little bit about human learning and retention, especially as people age or disease influences them. It's as simple as breathing to anybody with a little training, such as somebody with some specialty knowledge as a moderator in a web string devoted to a topic, that should naturally be there in the first place. It's like saying having someone who knows a bit about financing when they are selling a financial services app. If it's anything but absolutely easy to you, maybe you're in the wrong job, if you want it to be a success that is. To the right person it should be intuitively apparent once suggested. Otherwise they're just generic sales people. It's not that difficult what I'm suggesting at all, in fact it's an easy thing with virtually no marginal cost as well.
Mything the point: Some Thoughts on Living Well with PD
On the Holistic origin of Parkinson's
What can be done to make this website better?
Mucuna vs Sinemet
