There have been recent posts about Stanford University's development of a 'glove' that counteracts PD symptoms (and several other brain diseases!). This video was released in August, 2022.
Watch this 26 minute video interview of one of the Stanford researchers, Peter Tass (M.D., MDS, neurosurgeon, plus physics, math wizard!).
In their clinical studies... in just 3 months ... of applying this NON-INVASIVE 'vibration therapy' to the fingertips of their subjects...
80% (says doc) = MAJOR IMPROVEMENT!
1. NO side effects
2. PwP subjects wore the device 2 to 4 hours a day ...
After a few weeks the 'vibration dose' reduces to just 2-3 hours per week, says the researcher.
3. Seeking FDA approval now for a broader trial for PD (and essential tremor, dystonia, epilepsy) --
ALREADY APPROVED by the FDA for 'tinnitus' ringing-in-the-ear condition.
"The purpose of our study is to evaluate Vibrotactile Coordinated Reset stimulation (vCR) and its effects on motor ability within Parkinson's patients. vCR will be administered with a device called the VT Brain Glove. vCR is expected to provide patients with a non-invasive alternative to the most widely used treatments such as levodopa and or deep brain stimulation. This study will include a dedicated sham that will aid in understanding true treatment effects from vCR."
That is a great video. I like that the goal of the glove is un-syncing the brain. That is one of the main reasons I am researching Binaural Beats. Binaural Beats may be able to un-sync the brain. PD brains tend to get synced up.
the good doc was a bit hard to hear... and with his accent... hard to understand... but i listened and relistened to every word and his research is by far the MOST ENCOURAGING of any clinical study that i'm aware of... plus... NON-invasive! ... plus... just '3' months to SEE GOOD RESULTS! ... Christmas is coming early this year!
I listen to Binaural Beats every day. Are they helping? I don't know. I believe they SHOULD help so I keep using them. Here is my page on Binaural Beats page (it included free Binaural Beats files): rbd-pd-protocols.blogspot.c...
With PD the entire brain tends to get into a 20 or 25 HZ rhythm. You brain should have different frequencies in different parts. That study you linked to if aimed at 40 HZ. 40 HZ is what meditation gets you. I don't think that study is trying to get the entire brain to 40 HZ. I use 38 HZ in the binaural beats videos I listen to (and 6 HZ. I alternate between the two).
I tried a glove that plugged into a revitive device when hubby was first diagnosed as I thought it might bring sensation and dexterity back to his hands that don’t work.
I don’t know how similar it is in action. This is like a tens machine . He struggled to get gloves on and found them stressful to use back then so we have up as it was not worth the stress. I might have another go now though as he is more willing to try things recently. He is enjoying his red hat more and more and is pursuing more hand exercises and agrees to see a physio for a while which he resisted for ages. He might like to try it now.
yes I am pretty sure it does. He always wants it and swears it makes him feel better. And it seems to. I’m not sure how that translates to tangible benefits, more about feeling better.
A while back he stopped using it for a while and it was then he deteriorated but that might also have been other factors, but since wearing it again he is feeling good again, but again there were also other factors.
CUE1 uses the same way of desynchronisation techique and works miraculously.
Most of vibrotactile devices modulate Beta waves bursts in the brain. Beta waves are increased while we are still and decrease before and during movement. In PwPd the bursts of Beta wave are always high and CUE1 modulates (desynchronises) those waves the same way Ldopa modulates Beta waves and improves our symptoms.
I will be very excited and extremely happy for everyone if this is the breakthrough we have all been waiting for. Especially, as it's non invasive and free of side effects. I will also be heartbroken at the same time, as it is too late for my wonderful mum, who I lost in 2019 from complications of this evil disease.
I was skeptical until I watched the interview. Then I searched "Dr. Peter Tass Stanford Parkinson's glove" on YouTube and found more videos, including the one I have attached. My mind is blown. Once again, it seems that everything we "know" about Parkinson's (dopamine depletion, neuronal death, alpha synuclein, etc., etc.) is wrong.
yes, i also posted portions of this video above... as far as "everything we know about PD being wrong..." ... I'm not astute enough to make that observation... Just like many things in life have more than one solution... in all probability... it's the same with PD.
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We really don't care 'who' gets there 'first' --- right?
Good point, but I just volunteered to take part in the Phase 3 trial of Buntanetap and now I'm wondering why on Earth I would voluntarily ingest an experimental drug when I could wear a pair of gloves for a couple hours each day and apparently have a greater chance of success, especially considering I have a 33% chance of getting a placebo in the drug trial.
I think my reaction to this is similar to what it was for Loring. The difference, I think, is that for all the talk, Loring never actually implanted stem cells in human beings. Tass has actually tried his therapy on humans.
Yes. But as a punter with PD - it's frustrating that it takes so long to be delivered to the general PD population. As I told you, I first saw the video with the guy staggering towards the chair, and then marching confidently with swinging arms 4 years ago. It's very promising - but what are we waiting for?
And how many people have they tried it on, and what have their results been?
OMG! ... so i posted ... what i thought... was THREE great, hopeful postings the last few days all three have been .... dashed... (not quite 'down the toilet')
1. farnesol post
2. stanford university glove post
3. some new drug entering phase 2 --- FDA red flag
Im not sure why I am so frequently taken to be a young lady here. WTP was clearly a male bear for AA Milne. My wife says I need to change my aftershave. The glove and inhibikase are both on my "hot" list. It's just when you've been around a while you realise how maddeningly slow things are?
My opinion is you are doing the right thing. I didn't qualify for the Buntanetap trial. I am very excited about their phase 1 and phase 2 results. Please keep us up-to-date on your progress. GOOD LUCK!
I went to his website and downloaded some of his research articles that are freely available on Researchgate. They are quite impossible to understand, full of pages of mathematical formulas, but the diagrams give some clues as to what he is trying to do. As I understand it (and I could be quite wrong here), he uses a single wavelength of about 5 Hz and applies a phase shift for different fingers. He says that this stimulation goes up to neighbouring neurons that are usually synchronized in the PD brain. Because of the phase-shift, they are forced to desynchronize. (Boltupright will like that) They desynchronize in about 3 seconds. When you stop the stimulation, they resync over the next 5 seconds or so. He claims that by repeating this, these neurons gradually learn about the unsynchronised state and progressively move over to it. He doesn't use sine-wave vibrations but very sharp spike waves. It seems that the shape of the wave makes a difference, but I don''t understand that bit.
NOW, here's what I think we can do to test this ourselves. You can stimulate your fingers with a phase shift stimulation by rubbing your hands on a rough or uneven surface. If you rub your hands (or feet ) across a rough surface (tree bark, rough rendered wall, fine mesh grill etc), each finger and each millimetre of the finger surface will send the same stimulation with a phase shift of less than a second to the brain. If the surface is spiky rough, you will send a spiky signal to the brain. Not quite the engineered spiky vibration , but does it really matter?
Try it for a few minutes with your tremor hand and let me know...
Hello wriga ~ Thank you for your thoughts! I was just wondering since “Turban” man had 2-hour sessions a day, do you think that there will be some benefit with doing this for a few minutes?
Well... I've been doing something 'similar' for months... and YES YES YES... I find my 'internal tremors' have greatly reduced ... I've posted this several times here... I bought two large massagers from Amazon ($90) each ... like the one below .... They're much cheaper on eBay -- I've seen this exact model for as low as $53, new.
Anyway... I lay in bed with one of these on each side of me. I put the speed on 'low' (that's enough for me) and I grip the surface area with each hand... I also do this in the morning when I wake up...
Since I watched the videos above... I'm concentrating now on vibrating each 'hand' rather than my forearm or upper arms...
I'm far from 'healed.' I still get 100s and 100s of internal tremors daily...
And whether it's a "placebo effect" or not... There's no question that overall I am better.
p.s. But I'm also doing a million other things as well. So no one here really knows what is 'working' ... do we?
But we pretty much know when something is 'NOT' working, right?
"Treatment of Neurological Diseases: Dr. Tass reports of use of vibrotactile stimulation to apply Coordinated Reset Stimulation (CRS), which has been shown to cause long-lasting reduction of pathological synchronization in parkinsonian monkeys. researchgate.net/publicatio...
All you have to do is write the software, and that's it! Someone???
Treatment of Neurological Diseases: Dr. Tass reports of use of vibrotactile stimulation to apply Coordinated Reset Stimulation (CRS), which has been shown to cause long-lasting reduction of pathological synchronization in parkinsonian monkeys.
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